NFL Games This Sunday: Predictions, Odds, Picks, Best Bets for Week 18

The Week 18 NFL lineup for Sunday has lots in store. Among those contests is the Minnesota Vikings squaring off against the Detroit Lions.

Take a peek at our betting breakdown for the NFL's Week 18 action on Sunday.

Cowboys vs. Commanders

The Washington Commanders (11-5), who have the fifth-ranked scoring offense in the NFL (28.9 points per game), will try to take advantage of the Dallas Cowboys' (7-9) 31st-ranked scoring defense (27.8 points conceded per contest) when the Commanders visit the Cowboys on Sunday, Jan. 5 at AT&T Stadium. Kickoff is at 1 p.m. ET.

• Matchup: Washington Commanders at Dallas Cowboys
• Projected Favorite: Commanders (68.85% win probability)
• Spread: Washington (-7)
• Total: 43.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Dallas vs. Washington with FanDuel Sportsbook.

Buccaneers vs. Saints

The Tampa Bay Buccaneers (9-7) are set to take on the New Orleans Saints (5-11) at Raymond James Stadium on Sunday, Jan. 5 at 1 p.m. ET. In their previous contests, the Buccaneers took down the Panthers 48-14, and the Saints lost 25-10 to the Raiders.

• Matchup: New Orleans Saints at Tampa Bay Buccaneers
• Projected Favorite: Buccaneers (84.76% win probability)
• Spread: Tampa Bay (-14.5)
• Total: 44.5 -- Over: (-110) | Under: (-110)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Tampa Bay vs. New Orleans with FanDuel Sportsbook.

Titans vs. Texans

Nissan Stadium is the venue where the Tennessee Titans will take on the Houston Texans on Sunday, January 5, 2025.

• Matchup: Houston Texans at Tennessee Titans
• Projected Favorite: Titans (52.67% win probability)
• Spread: Tennessee (-1.5)
• Total: 36.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Tennessee vs. Houston with FanDuel Sportsbook.

Falcons vs. Panthers

The Carolina Panthers (4-12) and their worst run defense could struggle to stop the Atlanta Falcons (8-8) and Bijan Robinson, one of the NFL's top rushers, when the Panthers visit the Falcons at Mercedes-Benz Stadium on Jan. 5 at 1 p.m. ET.

• Matchup: Carolina Panthers at Atlanta Falcons
• Projected Favorite: Falcons (77.53% win probability)
• Spread: Atlanta (-7.5)
• Total: 48.5 -- Over: (-115) | Under: (-105)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Atlanta vs. Carolina with FanDuel Sportsbook.

Patriots vs. Bills

One of the best running backs in football will be featured when James Cook and the Buffalo Bills visit the New England Patriots on Sunday, January 5, 2025.

• Matchup: Buffalo Bills at New England Patriots
• Projected Favorite: Bills (73.60% win probability)
• Spread: Buffalo (-3.5)
• Total: 35.5 -- Over: (-106) | Under: (-114)
• Time: 1 p.m. ET
• Channel: CBS

Bet on New England vs. Buffalo with FanDuel Sportsbook.

Colts vs. Jaguars

One of the top pass-catchers in football will be on display when Brian Thomas Jr. and the Jacksonville Jaguars visit the Indianapolis Colts on Sunday, January 5, 2025.

• Matchup: Jacksonville Jaguars at Indianapolis Colts
• Projected Favorite: Colts (65.07% win probability)
• Spread: Indianapolis (-3.5)
• Total: 44.5 -- Over: (-108) | Under: (-112)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Indianapolis vs. Jacksonville with FanDuel Sportsbook.

Packers vs. Bears

Josh Jacobs will lead the Green Bay Packers into their battle against the Chicago Bears at Lambeau Field on Sunday at 1 p.m. ET.

• Matchup: Chicago Bears at Green Bay Packers
• Projected Favorite: Packers (87.21% win probability)
• Spread: Green Bay (-9.5)
• Total: 41.5 -- Over: (-106) | Under: (-114)
• Time: 1 p.m. ET
• Channel: FOX

Bet on Green Bay vs. Chicago with FanDuel Sportsbook.

Eagles vs. Giants

The 1 p.m. ET game on Jan. 5 between the New York Giants (3-13) and the Philadelphia Eagles (13-3) should be a fun matchup, as Malik Nabers has been one of the NFL's top receivers this season, and the Eagles have been a top-five pass defense, ranking first in the NFL with 176.4 passing yards surrendered per game.

• Matchup: New York Giants at Philadelphia Eagles
• Projected Favorite: Eagles (78.38% win probability)
• Spread: Philadelphia (-2.5)
• Total: 35.5 -- Over: (-105) | Under: (-115)
• Time: 1 p.m. ET
• Channel: CBS

Bet on Philadelphia vs. New York with FanDuel Sportsbook.

Raiders vs. Chargers

One of the best pass-catchers in football will be on display when Brock Bowers and the Las Vegas Raiders host the Los Angeles Chargers on Sunday, January 5, 2025.

• Matchup: Los Angeles Chargers at Las Vegas Raiders
• Projected Favorite: Chargers (70.87% win probability)
• Spread: Los Angeles (-6.5)
• Total: 42.5 -- Over: (-108) | Under: (-112)
• Time: 4:25 p.m. ET
• Channel: CBS

Bet on Las Vegas vs. Los Angeles with FanDuel Sportsbook.

Broncos vs. Chiefs

At 4:25 p.m. ET on Sunday, the Kansas City Chiefs play at the Denver Broncos.

• Matchup: Kansas City Chiefs at Denver Broncos
• Projected Favorite: Broncos (62.11% win probability)
• Spread: Denver (-10.5)
• Total: 40.5 -- Over: (-105) | Under: (-115)
• Time: 4:25 p.m. ET

Bet on Denver vs. Kansas City with FanDuel Sportsbook.

Jets vs. Dolphins

Devon Achane will lead the Miami Dolphins into their battle versus the New York Jets at MetLife Stadium, on Sunday at 4:25 p.m. ET.

• Matchup: Miami Dolphins at New York Jets
• Projected Favorite: Dolphins (54.63% win probability)
• Spread: New York (-1.5)
• Total: 37.5 -- Over: (-114) | Under: (-106)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on New York vs. Miami with FanDuel Sportsbook.

Rams vs. Seahawks

On Sunday at 4:25 p.m. ET, a pair of the best offensive players in football will be on show when wideout Jaxon Smith-Njigba and the Seattle Seahawks visit running back Kyren Williams and the Los Angeles Rams.

• Matchup: Seattle Seahawks at Los Angeles Rams
• Projected Favorite: Seahawks (56.32% win probability)
• Spread: Seattle (-7)
• Total: 38.5 -- Over: (-110) | Under: (-110)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Los Angeles vs. Seattle with FanDuel Sportsbook.

Cardinals vs. 49ers

The Arizona Cardinals (7-9) and the San Francisco 49ers (6-10), who were both defeated in their last tilt, will meet at 4:25 p.m. ET on Sunday, Jan. 5. In their previous games, the Cardinals lost 13-9 to the Rams, and the 49ers were taken down by the Lions 40-34.

• Matchup: San Francisco 49ers at Arizona Cardinals
• Projected Favorite: Cardinals (63.77% win probability)
• Spread: Arizona (-4.5)
• Total: 42.5 -- Over: (-105) | Under: (-115)
• Time: 4:25 p.m. ET
• Channel: FOX

Bet on Arizona vs. San Francisco with FanDuel Sportsbook.

Lions vs. Vikings

Against the Detroit Lions (14-2), who have the 31st-ranked pass defense this season, Justin Jefferson and the Minnesota Vikings (14-2) shouldn't have any trouble through the air when the two teams come together on Sunday, Jan. 5 at 8:20 p.m. ET. Jefferson has been one of the NFL's top receivers this year, ranking second-best in the league in receiving yards.

• Matchup: Minnesota Vikings at Detroit Lions
• Projected Favorite: Lions (68.87% win probability)
• Spread: Detroit (-2.5)
• Total: 56.5 -- Over: (-108) | Under: (-112)
• Time: 8:20 p.m. ET
• Channel: NBC

Bet on Detroit vs. Minnesota with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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