MLB Predictions Today: 3 MLB Best Bets and Picks for Tuesday, September 15, 2026

MLB Betting Picks in Summary

• Seiya Suzuki to Record 2+ H/R/RBI (-125)
• Mickey Moniak to Hit a Home Run (+430)
• Logan Gilbert Over 6.5 Strikeouts (-115)

Baseball has you covered if you want a large inventory of options to bet.

From moneylines to player props to NRFI wagers, we have plenty of ways each day to bet the long, arduous MLB schedule.

Using the MLB odds at FanDuel Sportsbook, what are the best MLB bets for today?

This article includes some of the top bets from our other MLB content. All MLB odds via FanDuel, and they may change after this article is published.

MLB Picks and Predictions for Today

Seiya Suzuki to Record 2+ H/R/RBI (-125)

Braves vs. Cubs, 7:41 p.m. ET

Seiya Suzuki is mauling lefties this season, and he’s up against Martin Perez today.

For the campaign, Suzuki has a .416 wOBA against LHPs with a 40.4% fly-ball rate in the split.

He also hits the ball much better at home, posting a 38.3% hard-hit rate and .398 wOBA at Wrigley, compared to a 31.1% hard-hit rate and .334 wOBA on the road.

Perez has a 17.9% K rate and 4.79 SIERA on the season, so he’s a pretty friendly matchup. His strikeout rate against right-handed hitters is just 16.8%.

Home Run Prediction: Mickey Moniak (+430)

Padres at Rockies, 8:41 p.m. ET

Mickey Moniak has pieced together another quality year, and he’s just two homers off his career high, which he set just a season ago.

I like him tonight against righty Walker Buehler.

Moniak has 22 bombs this season, 19 of which have come versus right-handers. On top of that, of those 22 home runs, 18 were hit at Coors. Those two boxes — at home and against a RHP — are checked today.

Buehler has been respectable this campaign. However, he’s still got a 4.35 SIERA and 8.2% swinging-strike rate. Lefties have tagged him for a .342 wOBA, and he’s allowed 1.31 homers per nine away from pitcher-friendly Petco.

Logan Gilbert Over 6.5 Strikeouts (-115)

Mariners vs. Angels, 9:39 p.m. ET

While Logan Gilbert‘s results have been lacking, there’s a lot to like under the hood, and he’s got a lovely matchup tonight versus the Los Angeles Angels.

Gilbert’s ERA over his past six starts is 4.96, but his expected ERA is 3.29. A comically high 24.2% home-run-to-fly-ball rate is the main culprit.

In that six-start span, Gilbert owns a sparkling 30.7% K rate and 14.2% swinging-strike rate. He’s missing bats at an elite level, and he can keep rolling against a Halos squad that has the third-highest strikeout rate over the previous 30 days (26.1%).

MLB Betting Frequently Asked Questions

What are MLB player prop bets?

MLB player prop bets are wagers on specific statistical outcomes tied to individual players during a game — not on which team wins or loses. You might bet on how many strikeouts a starting pitcher records, whether a shortstop gets a hit, or how many total bases an outfielder accumulates.

Because they are isolated to a single player's performance, props let you apply focused knowledge about matchups, recent form, and ballpark conditions rather than predicting the full game result.

What types of MLB player props are available?

FanDuel offers a wide menu of MLB props. The most common categories include:

• Pitcher strikeouts
• Batter hits
• Home runs
• Total bases
• RBIs
• Stolen bases
• Pitcher outs recorded

What does +310 mean on an MLB home run prop bet?

A +310 line means a $100 bet returns $310 in profit if the player homers. You can bet any amount — a $10 bet at +310 returns $31 in profit. The number reflects the implied probability the sportsbook assigns to the event (roughly 24% for +310 odds).

What does "total bases" mean as a prop bet?

The total bases prop counts the bases a batter earns from hits in a single game:

• Single = 1 base
• Double = 2 bases
• Triple = 3 bases
• Home run = 4 bases

Walks, hit-by-pitches, and stolen bases do not count. A typical total bases line is set at 1.5 or 2.5. Betting over 1.5 means you need at least a double, or two singles.

Which MLB bets stand out to you today? Check out FanDuel Sportsbook's MLB odds to see the full menu of options.

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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author’s advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.