Mississippi State vs Wake Forest Prediction, Odds, Picks, Best Bets for Duke's Mayo Bowl 2025

NCAA football action on Friday includes the Mississippi State Bulldogs taking on the Wake Forest Demon Deacons.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Mississippi State vs Wake Forest Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Mississippi State: (-132) | Wake Forest: (+110)
• Spread: Mississippi State: -2.5 (-110) | Wake Forest: +2.5 (-110)
• Total: 56.5 -- Over: (-110) | Under: (-110)

Mississippi State vs Wake Forest Betting Trends

• Mississippi State is 8-4-0 against the spread this season.
• As 2.5-point favorites or more, Mississippi State is 3-0 against the spread.
• Out of 12 Mississippi State games so far this season, six have gone over the total.
• Wake Forest has eight wins in 12 contests against the spread this year.
• Wake Forest is 4-3 as 2.5-point or bigger underdogs in 2025.
• Of 12 Wake Forest games so far this year, seven have hit the over.

Mississippi State vs Wake Forest Point Spread

Mississippi State is favored by 2.5 points (-110 to cover) in this matchup. Wake Forest, the underdog, is -110.

Mississippi State vs Wake Forest Over/Under

An over/under of 56.5 has been set for Mississippi State-Wake Forest on Jan. 2, with the over being -110 and the under -110.

Mississippi State vs Wake Forest Moneyline

Wake Forest is the underdog, +110 on the moneyline, while Mississippi State is a -132 favorite.

Mississippi State vs. Wake Forest Points Insights

Mississippi State vs. Wake Forest Game Info

• Game day: Friday, January 2, 2026
• Game time: 8 p.m. ET
• TV channel: ESPN
• Location: Charlotte, North Carolina
• Stadium: Bank of America Stadium

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Check out even more in-depth Mississippi State vs. Wake Forest analysis on FanDuel Research.