Minnesota vs Buffalo Prediction, Odds, Picks, Best Bets for Week 1 2025

On Thursday in college football, the Minnesota Golden Gophers are playing the Buffalo Bulls.
Get the latest NCAA football odds ahead of this game on FanDuel Sportsbook.
Minnesota vs Buffalo Odds & Spread
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- All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: Minnesota: (-1205) | Buffalo: (+740)
- Spread: Minnesota: -17.5 (-110) | Buffalo: +17.5 (-110)
- Total: 44.5 -- Over: (-110) | Under: (-110)
Minnesota vs Buffalo Betting Trends
- Against the spread, Minnesota went 9-3-1 last season.
- Minnesota covered every time (2-0) as a 17.5-point or higher favorite last year.
- In 13 Minnesota games last year, six hit the over.
- Buffalo posted a 7-5-0 record against the spread last year.
- Buffalo had no wins ATS (0-1) as underdogs of 17.5 points or greater last year.
- In 12 Buffalo games last year, eight of them hit the over.
Minnesota vs Buffalo Prediction & Pick
All college football win probability predictions and picks are according to numberFire.
Prediction: Golden Gophers win (92.7%)
Minnesota vs Buffalo Point Spread
Buffalo is a 17.5-point underdog against Minnesota. Buffalo is -110 to cover the spread, and Minnesota is -110.
Minnesota vs Buffalo Over/Under
The over/under for the Minnesota versus Buffalo game on Aug. 28 has been set at 44.5, with -110 odds on the over and -110 odds on the under.
Minnesota vs Buffalo Moneyline
Looking at the moneyline for Minnesota-Buffalo, Minnesota is the favorite at -1205, and Buffalo is +740.
Minnesota vs. Buffalo Points Insights
- The Golden Gophers' average implied point total last season was 4.9 fewer points than their implied total in Thursday's game (26.1 implied points on average compared to 31 implied points in this game).
- The Bulls' average implied point total last season (28.7 points) is 14.7 points higher than their implied total in this matchup (14 points).
Minnesota vs. Buffalo Game Info
- Game day: Thursday, August 28, 2025
- Game time: 8 p.m. ET
- TV channel: Fox Sports 1
- Location: Minneapolis, Minnesota
- Stadium: Huntington Bank Stadium
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Check out even more in-depth Minnesota vs. Buffalo analysis on FanDuel Research.