Michigan State vs Western Michigan Prediction, Odds, Picks, Best Bets for Week 1 2025

The Michigan State Spartans versus the Western Michigan Broncos is on the college football schedule for Friday.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Michigan State vs Western Michigan Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Michigan State: (-1449) | Western Michigan: (+810)
• Spread: Michigan State: -20.5 (-110) | Western Michigan: +20.5 (-110)
• Total: 49.5 -- Over: (-115) | Under: (-105)

Michigan State vs Western Michigan Betting Trends

• Michigan State's record against the spread last year was 4-8-0.
• Michigan State went winless ATS (0-1) when playing as at least 20.5-point favorites last year.
• Last year, six of Michigan State's 12 games hit the over.
• Western Michigan beat the spread five times in 13 games last season.
• As a 20.5-point underdog or greater, Western Michigan had one win ATS (1-1) last year.
• Western Michigan had seven of its 13 games hit the over last season.

Michigan State vs Western Michigan Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Spartans win (87.6%)

Michigan State vs Western Michigan Point Spread

Western Michigan is a 20.5-point underdog against Michigan State. Western Michigan is -110 to cover the spread, and Michigan State is -110.

Michigan State vs Western Michigan Over/Under

Michigan State versus Western Michigan, on Aug. 29, has an over/under of 49.5, with the over being -115 and the under -105.

Michigan State vs Western Michigan Moneyline

Michigan State is a -1449 favorite on the moneyline, while Western Michigan is a +810 underdog.

Michigan State vs. Western Michigan Points Insights

• The Spartans' average implied point total last season was 5.2 fewer points than their implied total in Friday's game (29.8 implied points on average compared to 35 implied points in this game).
• The Broncos' average implied point total last season (34.1 points) is 19.1 points higher than their implied total in this matchup (15 points).

Michigan State vs. Western Michigan Game Info

• Game day: Friday, August 29, 2025
• Game time: 7 p.m. ET
• TV channel: Fox Sports 1
• Location: East Lansing, Michigan
• Stadium: Spartan Stadium

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Check out even more in-depth Michigan State vs. Western Michigan analysis on FanDuel Research.