Mariners vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 6

Odds updated as of 9:12 p.m.

On Wednesday in MLB, the Seattle Mariners are up against the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this matchup.

Mariners vs White Sox Game Info

• Seattle Mariners (61-53) vs. Chicago White Sox (42-71)
• Date: Wednesday, August 6, 2025
• Time: 9:40 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: MLB Network, ROOT Sports NW, and CHSN

Mariners vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-270) | CHW: (+220)
• Spread: SEA: -1.5 (-122) | CHW: +1.5 (+102)
• Total: 7.5 -- Over: (-106) | Under: (-114)

Mariners vs White Sox Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 6-5, 4.12 ERA vs Jonathan Cannon (White Sox) - 4-8, 4.77 ERA

The probable starters are George Kirby (6-5) for the Mariners and Jonathan Cannon (4-8) for the White Sox. Kirby's team is 5-7-0 against the spread this season in his starts. Kirby's team is 6-4 this season when he starts and they are the moneyline favorite. The White Sox are 8-8-0 against the spread when Cannon starts. The White Sox have been the moneyline underdog in 16 of Cannon's starts this season, and they went 6-10 in those games.

Mariners vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (70.5%)

Mariners vs White Sox Moneyline

• Seattle is a -270 favorite on the moneyline, while Chicago is a +220 underdog on the road.

Mariners vs White Sox Spread

• The White Sox are +1.5 on the run line against the Mariners. The White Sox are +102 to cover, and the Mariners are -122.

Mariners vs White Sox Over/Under

• A total of 7.5 runs has been set for the Mariners-White Sox game on Aug. 6, with the over available at -106 and the under at -114.

Bet on Seattle Mariners vs. Chicago White Sox on FanDuel today!

Mariners vs White Sox Betting Trends

• The Mariners have come away with 41 wins in the 75 contests they have been listed as the favorites in this season.
• Seattle has played as a favorite of -270 or more just one time this year and came away with a loss in that game.
• The Mariners and their opponents have gone over in 58 of their 111 games with a total set by sportsbooks this season.
• The Mariners are 48-63-0 against the spread in their 111 games with a line set by sportsbooks this season.
• The White Sox have won 36.2% of the games this season they were the underdog on the moneyline (38-67).
• Chicago has a record of 1-9 when playing as a moneyline underdog with odds of +220 or longer (10%).
• The White Sox have played in 108 games with an over/under set, and have combined with their opponents to go over the total 48 times (48-53-7).
• The White Sox have covered 55.6% of their games this season, going 60-48-0 ATS.

Mariners Player Leaders

• Cal Raleigh leads Seattle with 104 hits and an OBP of .356 this season. He has a .249 batting average and a slugging percentage of .590.
• Among all qualified hitters, he ranks 100th in batting average, his on-base percentage ranks 33rd, and he is third in slugging.
• Eugenio Suarez is hitting .243 with 20 doubles, 37 home runs and 30 walks. He's slugging .565 with an on-base percentage of .314.
• Among qualified hitters, he is 115th in batting average, 109th in on-base percentage and fifth in slugging percentage.
• Josh Naylor is batting .287 with a .444 slugging percentage and 63 RBI this year.
• Julio Rodriguez leads Seattle with a slugging percentage of .435, fueled by 42 extra-base hits.
• Rodriguez has safely hit in three games in a row. During his last five outings he is batting .227 with a double, a home run and three RBIs.

White Sox Player Leaders

• Andrew Benintendi is hitting .231 with 13 doubles, two triples, 14 home runs and 29 walks. He's slugging .431 with an on-base percentage of .299.
• Luis Robert is batting .219 with nine doubles, 12 home runs and 36 walks. He's slugging .362 with an on-base percentage of .301.
• Including all qualified hitters, his batting average puts him 157th, his on-base percentage ranks 133rd, and he is 145th in slugging.
• Lenyn Sosa has racked up a slugging percentage of .439 and has 96 hits, both team-high numbers for the White Sox.
• Chase Meidroth has a .330 OBP to pace his team.

Mariners vs White Sox Head to Head

• 8/5/2025: 8-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -250, Underdog Moneyline: +205)
• 5/21/2025: 6-5 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 5/19/2025: 5-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 7/28/2024: 6-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/27/2024: 6-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/26/2024: 10-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/13/2024: 3-2 CHW (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/12/2024: 2-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 6/11/2024: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 6/10/2024: 8-4 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -215, Underdog Moneyline: +180)

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