Mariners vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for May 20

Odds updated as of 12:13 p.m.

The Tuesday schedule in MLB includes a matchup between the Seattle Mariners and the Chicago White Sox.

We've got you covered, in terms of the vital info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Mariners vs White Sox Game Info

• Seattle Mariners (27-19) vs. Chicago White Sox (14-34)
• Date: Tuesday, May 20, 2025
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and ROOT Sports NW

Mariners vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-184) | CHW: (+154)
• Spread: SEA: -1.5 (-110) | CHW: +1.5 (-110)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Mariners vs White Sox Probable Starting Pitchers

Probable Pitchers: TBA (Mariners) vs Bryse Wilson (White Sox) - 0-2, 0.00 ERA

Wilson (0-2) will start for the White Sox. As of this writing, there's been no pitching decision announced by the Mariners. The White Sox have gone 2-2-0 ATS in Wilson's four starts that had a set spread. The White Sox are 2-2 in Wilson's four starts this season that they were the underdog on the moneyline.

Mariners vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (62.9%)

Mariners vs White Sox Moneyline

• Seattle is the favorite, -184 on the moneyline, while Chicago is a +154 underdog despite being at home.

Mariners vs White Sox Spread

• The Mariners are at the White Sox and are favored by 1.5 runs on the spread. The Mariners are -110 to cover the runline, with the White Sox being -110.

Mariners vs White Sox Over/Under

• Mariners versus White Sox, on May 20, has an over/under of 8.5, with the over being -100 and the under -122.

Bet on Seattle Mariners vs. Chicago White Sox on FanDuel today!

Mariners vs White Sox Betting Trends

• The Mariners have won in 16, or 59.3%, of the 27 contests they have been named as odds-on favorites in this year.
• Seattle has a record of 3-2 in contests when bookmakers favor them by -184 or more on the moneyline.
• The Mariners and their opponents have hit the over in 25 of their 46 games with a total set by oddsmakers this season.
• In 46 games with a line this season, the Mariners have a mark of 24-22-0 against the spread.
• The White Sox have put together a 13-33 record in games they were the underdog on the moneyline (winning 28.3% of those games).
• In games it has played as a moneyline underdog with odds of +154 or longer, Chicago has a 5-24 record (winning only 17.2% of its games).
• The White Sox have combined with opponents to hit the over on the total 21 times this season for a 21-23-3 record against the over/under.
• The White Sox have collected a 23-24-0 record ATS this season.

Mariners Player Leaders

• Cal Raleigh has 40 hits, which is tops among Seattle hitters this season, while batting .241 with 23 extra-base hits. He has an on-base percentage of .362 and a slugging percentage of .560.
• Among all qualified hitters in the majors, his batting average ranks 101st, his on-base percentage ranks 47th, and he is 11th in slugging.
• Julio Rodriguez has an OPS of .724, fueled by an OBP of .313 and a team-best slugging percentage of .412 this season. He's batting .235.
• Among qualified hitters, his batting average ranks him 115th, his on-base percentage 105th, and his slugging percentage 88th.
• Rodriguez has picked up a hit in seven straight games. In his last 10 outings he is batting .262 with a double, two home runs and eight RBIs.
• Jorge Polanco has 37 hits this season and has a slash line of .314/.359/.619.
• Randy Arozarena is batting .236 with a .372 OBP and 21 RBI for Seattle this season.

White Sox Player Leaders

• Miguel Vargas has accumulated 39 hits with a .321 on-base percentage, leading the White Sox in both categories. He's batting .239 and slugging .411.
• Including all the qualifying hitters in MLB, he ranks 109th in batting average, 95th in on-base percentage and 91st in slugging percentage.
• Luis Robert is batting .186 with four doubles, five home runs and 21 walks. He's slugging .308 with an on-base percentage of .281.
• He is 159th in batting average, 137th in on-base percentage and 156th in slugging percentage in MLB.
• Chase Meidroth is batting .286 with three doubles, a home run and 12 walks.
• Andrew Vaughn is hitting .185 with eight doubles, five home runs and seven walks.

Mariners vs White Sox Head to Head

• 5/19/2025: 5-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 7/28/2024: 6-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/27/2024: 6-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 7/26/2024: 10-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 6/13/2024: 3-2 CHW (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 6/12/2024: 2-1 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 6/11/2024: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 6/10/2024: 8-4 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 8/23/2023: 5-4 CHW (Favorite: Mariners, Spread: -1.5, Total: 9.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/22/2023: 6-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!