Mariners vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for March 27

Odds updated as of 6:13 a.m.

On Friday in MLB, the Seattle Mariners are playing the Cleveland Guardians.

We've got you covered, in terms of the vital info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Mariners vs Guardians Game Info

• Seattle Mariners (0-1) vs. Cleveland Guardians (1-0)
• Date: Friday, March 27, 2026
• Time: 9:45 p.m. ET
• Venue: T-Mobile Park -- Seattle, Washington
• Coverage: Apple TV+

Mariners vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-180) | CLE: (+152)
• Spread: SEA: -1.5 (+122) | CLE: +1.5 (-146)
• Total: 7 -- Over: (-115) | Under: (-105)

Mariners vs Guardians Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 0-0, 0.00 ERA vs Gavin Williams (Guardians) - 0-0, 0.00 ERA

The Mariners will give the nod to George Kirby against the Guardians and Gavin Williams. Kirby and his team were 12-15-0 against the spread when he pitched last season. Kirby and his team were 11-11 when he pitched and they were the moneyline favorite. Last season when Williams pitched his team went 18-14-0 against the spread. Williams and his team went 11-11 in games he pitched when they were the underdog on the moneyline a season ago.

Mariners vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (68.9%)

Mariners vs Guardians Moneyline

• Cleveland is a +152 underdog on the moneyline, while Seattle is a -180 favorite at home.

Mariners vs Guardians Spread

• The Guardians are at +1.5 on the runline against the Mariners. The Guardians are -146 to cover the spread, and the Mariners are +122.

Mariners vs Guardians Over/Under

• Mariners versus Guardians, on March 27, has an over/under of 7, with the over being -115 and the under -105.

Bet on Seattle Mariners vs. Cleveland Guardians on FanDuel today!

Mariners vs Guardians Betting Trends

• The Mariners won in 66, or 57.9%, of the 114 contests they were named as odds-on favorites in the last year.
• Last season Seattle came away with a win 21 times in 25 chances when named as a favorite of at least -180 or shorter on the moneyline.
• The Mariners and their opponents hit the over in 91 of their 168 games with a total last season.
• The Guardians compiled a 41-47 record in games last season when they were listed as the moneyline underdog (winning 46.6% of those games).
• Cleveland went 4-8 in games it played as a moneyline underdog with odds of +152 or longer (33.3%).
• The Guardians played in 161 games with a set over/under last season, and combined with their opponents to go over the total 69 times (69-85-7).

Mariners Player Leaders

• Cal Raleigh had 147 hits and an OBP of .359 last season.
• Julio Rodriguez had an OPS of .798, fueled by an OBP of .324 and a slugging percentage of .474.
• Josh Naylor ended his last campaign with 160 hits, an OBP of .353, plus a slugging percentage of .462.
• Randy Arozarena slashed .238/.334/.426 and finished with an OPS of .760.

Guardians Player Leaders

• Jose Ramirez had an on-base percentage of .360 and had 168 hits last season.
• Steven Kwan slugged .374 while batting .272.
• Kyle Manzardo hit .234 with 19 doubles, two triples, 27 home runs and 48 walks a season ago.
• Angel Martinez hit .224 with 23 doubles, two triples, 11 home runs and 23 walks.

Mariners vs Guardians Head to Head

• 3/26/2026: 6-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 6.5, Favorite Moneyline: -188, Underdog Moneyline: +158)
• 8/31/2025: 4-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/30/2025: 4-3 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/29/2025: 5-4 CLE (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/15/2025: 6-0 SEA (Favorite: Mariners, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 6/14/2025: 4-3 SEA (Favorite: Mariners, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/13/2025: 7-2 SEA (Favorite: Mariners, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/20/2024: 6-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/19/2024: 8-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 6/18/2024: 8-5 SEA (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)

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