Astros vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for March 27

Odds updated as of 6:12 a.m.

The Houston Astros are among the MLB teams in action on Friday, up against the Los Angeles Angels.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this matchup.

Astros vs Angels Game Info

• Houston Astros (0-1) vs. Los Angeles Angels (1-0)
• Date: Friday, March 27, 2026
• Time: 8:15 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: Apple TV+

Astros vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-168) | LAA: (+142)
• Spread: HOU: -1.5 (+128) | LAA: +1.5 (-154)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Astros vs Angels Probable Starting Pitchers

Probable Pitchers: Mike Burrows (Astros) - 0-0, 0.00 ERA vs Yusei Kikuchi (Angels) - 0-0, 0.00 ERA

The Astros will call on Mike Burrows versus the Angels and Yusei Kikuchi. Burrows and his team were 11-8-0 ATS in games he pitched last year. Burrows and his team had a 3-3 record when he pitched as a favorite last season. Last season Kikuchi and his team went 18-15-0 against the spread when he pitched. Kikuchi and his team went 7-14 in the 21 games he appeared in when they were the moneyline underdog a season ago.

Astros vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (66%)

Astros vs Angels Moneyline

• Los Angeles is a +142 underdog on the moneyline, while Houston is a -168 favorite at home.

Astros vs Angels Spread

• The Astros are favored by 1.5 runs at home versus the Angels. The Astros are +128 to cover the spread, while the Angels are -154.

Astros vs Angels Over/Under

• The over/under for the Astros versus Angels game on March 27 has been set at 8.5, with -110 odds on the over and -110 odds on the under.

Bet on Houston Astros vs. Los Angeles Angels on FanDuel today!

Astros vs Angels Betting Trends

• The Astros came away with 53 wins in the 99 contests they were listed as the favorites last season.
• Last season Houston came away with a win nine times in 18 chances when named as a favorite of at least -168 or shorter on the moneyline.
• The Astros and their opponents hit the over in 72 of their 161 games with a total last season.
• The Angels were the moneyline underdog 121 times last season. They went 52-69 in those games.
• Los Angeles went 18-24 when playing as a moneyline underdog with odds of +142 or longer (42.9%).
• The Angels combined with their opponents to go over the total 84 times last season for an 84-71-5 record against the over/under.

Astros Player Leaders

• Last season, Jose Altuve finished with a slugging percentage of .442, fueled by 51 extra-base hits.
• Jeremy Pena finished with an OBP of .363 and 150 total hits.
• Yainer Diaz ended his last campaign with 139 hits, an OBP of .284, plus a slugging percentage of .417.
• Christian Walker slashed .238/.297/.421 and finished with an OPS of .717.

Angels Player Leaders

• Jo Adell had 124 hits and a batting average of .236 a season ago.
• Nolan Schanuel had a .389 slugging percentage while batting .264.
• Zach Neto accumulated a .474 slugging percentage and a .257 batting average last year.
• Mike Trout had a .359 on-base percentage and batted .232.

Astros vs Angels Head to Head

• 3/26/2026: 3-0 LAA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/28/2025: 6-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/27/2025: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 9/26/2025: 4-3 LAA (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/1/2025: 8-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/31/2025: 3-0 LAA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/30/2025: 4-1 LAA (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 8/29/2025: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/22/2025: 8-7 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/21/2025: 9-1 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)

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