Mariners vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 24

Odds updated as of 6:13 a.m.

The Seattle Mariners will face the St. Louis Cardinals in MLB action on Friday.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Mariners vs Cardinals Game Info

• Seattle Mariners (11-15) vs. St. Louis Cardinals (14-10)
• Date: Friday, April 24, 2026
• Time: 8:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and Mariners.TV

Mariners vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SEA: (-162) | STL: (+136)
• Spread: SEA: -1.5 (+106) | STL: +1.5 (-128)
• Total: 8 -- Over: (-105) | Under: (-115)

Mariners vs Cardinals Probable Starting Pitchers

Probable Pitchers: George Kirby (Mariners) - 3-2, 2.97 ERA vs Andre Pallante (Cardinals) - 2-1, 4.05 ERA

This contest's pitching matchup is set, as the Mariners will send George Kirby (3-2) to the mound, while Andre Pallante (2-1) will take the ball for the Cardinals. Kirby's team is 3-2-0 against the spread this season in his starts. Kirby's team has a record of 3-2 this season when he starts and they are the favorite on the moneyline. The Cardinals have a 2-2-0 ATS record in Pallante's four starts with a set spread. The Cardinals have a 2-1 record in Pallante's three starts this season when they were the moneyline underdog.

Mariners vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mariners win (53.9%)

Mariners vs Cardinals Moneyline

• Looking at the moneyline for Cardinals-Mariners, St. Louis is the underdog at +136, and Seattle is -162 playing on the road.

Mariners vs Cardinals Spread

• The Cardinals are hosting the Mariners, and are +1.5 on the runline. The Cardinals are +106 to cover the spread, and the Mariners are -128.

Mariners vs Cardinals Over/Under

• A total of 8 runs has been set for the Mariners-Cardinals game on April 24, with the over available at -105 and the under at -115.

Bet on Seattle Mariners vs. St. Louis Cardinals on FanDuel today!

Mariners vs Cardinals Betting Trends

• The Mariners have come away with 10 wins in the 22 contests they have been listed as the favorites in this season.
• Seattle has a record of 5-4 in contests when bookmakers favor them by -162 or more on the moneyline.
• The Mariners and their opponents have hit the over in 12 of their 26 games with a total set by oddsmakers this season.
• In 26 games with a line this season, the Mariners have a mark of 9-17-0 against the spread.
• The Cardinals are 12-9 in games they were the underdog on the moneyline (winning 57.1% of those games).
• When playing as a moneyline underdog with odds of +136 or longer, St. Louis has a 1-2 record (winning just 33.3% of its games).
• In the 24 games bookmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 13 times (13-10-1).
• The Cardinals have covered 54.2% of their games this season, going 13-11-0 against the spread.

Mariners Player Leaders

• Randy Arozarena has 27 hits and an OBP of .385 to go with a slugging percentage of .419. All three of those stats lead Seattle hitters this season. He has a .290 batting average, as well.
• He is 32nd in batting average, 22nd in on-base percentage, and 79th in slugging among qualifying hitters in MLB.
• Arozarena hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .316 with two doubles, a home run and three RBIs.
• Cole Young has two doubles, a triple, two home runs and 11 walks. He's batting .233 and slugging .344 with an on-base percentage of .324.
• He is 116th in batting average, 109th in on-base percentage and 132nd in slugging in the major leagues.
• Cal Raleigh is batting .198 with a .386 slugging percentage and 14 RBI this year.
• Raleigh brings a four-game hitting streak into this game. In his last five games he is hitting .333 with a double, three home runs, two walks and three RBIs.
• Luke Raley is batting .292 with a .354 OBP and 13 RBI for Seattle this season.

Cardinals Player Leaders

• Jordan Walker has accumulated a slugging percentage of .607 and has 26 hits, both team-high marks for the Cardinals. He's batting .292 and with an on-base percentage of .357.
• Including all the qualified hitters in MLB, his batting average ranks 29th, his on-base percentage is 54th, and he is fifth in slugging.
• Alec Burleson is batting .278 with six doubles, three home runs and 12 walks. He's slugging .444 with an on-base percentage of .359.
• Including all qualifying hitters, he ranks 47th in batting average, 51st in on-base percentage and 57th in slugging percentage.
• Ivan Herrera has racked up a team-best .387 on-base percentage.
• JJ Wetherholt is hitting .218 with two doubles, three home runs and 15 walks.

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