LSU vs Alabama Prediction, Odds, Picks, Best Bets for Week 10 2026

Saturday's slate in college football includes a matchup between the LSU Tigers and the Alabama Crimson Tide.

Get the latest NCAA football odds ahead of this matchup on FanDuel Sportsbook.

LSU vs Alabama Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LSU: (-225) | Alabama: (+188)
• Spread: LSU: -5.5 (-122) | Alabama: +5.5 (100)
• Total: 52.5 -- Over: (-112) | Under: (-108)

LSU vs Alabama Betting Trends

• LSU has covered the spread four times in eight games.
• As 5.5-point favorites or more, LSU is 4-3 against the spread.
• LSU has played eight games this year, and five of them have hit the over.
• Against the spread, Alabama is 4-4-0 this season.
• Of eight Alabama games so far this year, six have hit the over.

LSU vs Alabama Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Tigers win (66.9%)

LSU vs Alabama Point Spread

LSU is a 5.5-point favorite against Alabama. LSU is -122 to cover the spread, and Alabama is +100.

LSU vs Alabama Over/Under

An over/under of 52.5 has been set for LSU-Alabama on Nov. 7, with the over being -112 and the under -108.

LSU vs Alabama Moneyline

LSU is the favorite, -225 on the moneyline, while Alabama is a +188 underdog.

LSU vs. Alabama Points Insights

LSU vs. Alabama Game Info

• Game day: Saturday, November 7, 2026
• Game time: 3:30 p.m. ET
• TV channel: ABC
• Location: Baton Rouge, Louisiana
• Stadium: Tiger Stadium

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Check out even more in-depth LSU vs. Alabama analysis on FanDuel Research.