Louisville vs Bowling Green Prediction, Odds, Picks, Best Bets for Week 4 2025

The Louisville Cardinals are among the college football teams in action on Saturday, up against the Bowling Green Falcons.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding today's NCAA football betting odds.

Louisville vs Bowling Green Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Louisville: (-4545) | Bowling Green: (+1600)
• Spread: Louisville: -26.5 (-120) | Bowling Green: +26.5 (-102)
• Total: 52.5 -- Over: (-115) | Under: (-105)

Louisville vs Bowling Green Betting Trends

• Louisville hasn't won a game against the spread this season.
• Louisville has no wins ATS (0-1) as a 26.5-point favorite or greater this year.
• One of Louisville's two games this season has hit the over.
• Bowling Green has posted two wins against the spread this season.
• One Bowling Green game (out of three) has gone over the point total this season.

Louisville vs Bowling Green Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (89.1%)

Louisville vs Bowling Green Point Spread

Louisville is favored by 26.5 points over Bowling Green. Louisville is -120 to cover the spread, with Bowling Green being -102.

Louisville vs Bowling Green Over/Under

A combined point total of 52.5 has been set for Louisville-Bowling Green on Sept. 20, with the over at -115 and the under at -105.

Louisville vs Bowling Green Moneyline

The Louisville vs Bowling Green moneyline has Louisville as a -4545 favorite, while Bowling Green is a +1600 underdog.

Louisville vs. Bowling Green Points Insights

Louisville vs. Bowling Green Game Info

• Game day: Saturday, September 20, 2025
• Game time: 12 p.m. ET
• TV channel: ACC Network
• Location: Louisville, Kentucky
• Stadium: L&N Federal Credit Union Stadium

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