Louisiana vs Southern Miss Prediction, Odds, Picks, Best Bets for Week 8 2026

College football's Saturday slate includes the Louisiana Ragin' Cajuns facing the Southern Miss Golden Eagles.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Louisiana vs Southern Miss Odds & Spread

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• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Louisiana: (-400) | Southern Miss: (+310)
• Spread: Louisiana: -10.5 (-105) | Southern Miss: +10.5 (-115)
• Total: 52.5 -- Over: (-110) | Under: (-110)

Louisiana vs Southern Miss Betting Trends

• Louisiana has beaten the spread six times in seven games.
• Louisiana has yet to lose ATS (2-0) as a 10.5-point favorite or greater this year.
• Two of Louisiana's seven games have gone over the point total.
• Southern Miss has won twice against the spread this year.
• As a 10.5-point underdog or more, Southern Miss has one win ATS (1-1) this year.
• Southern Miss has seen three of its six games go over the point total.

Louisiana vs Southern Miss Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Ragin' Cajuns win (78%)

Louisiana vs Southern Miss Point Spread

Southern Miss is the underdog by 10.5 points against Louisiana. Southern Miss is -105 to cover the spread, and Louisiana is -115.

Louisiana vs Southern Miss Over/Under

Louisiana versus Southern Miss on Oct. 24 has an over/under of 52.5 points, with the over -110 and the under -110.

Louisiana vs Southern Miss Moneyline

Louisiana is a -400 favorite on the moneyline, while Southern Miss is a +310 underdog.

Louisiana vs. Southern Miss Points Insights

Louisiana vs. Southern Miss Game Info

• Game day: Saturday, October 24, 2026
• Game time: 5 p.m. ET
• TV channel: ESPN+
• Location: Hattiesburg, Mississippi
• Stadium: M.M. Roberts Stadium

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