Lions vs 49ers Prediction, Odds, Picks, Best Bets for NFL Week 17 Monday Night Football

The Detroit Lions are among the NFL teams busy on Monday, up against the San Francisco 49ers.

All the info you need is below, in order to make a smart wager on this matchup at FanDuel Sportsbook.

Lions vs 49ers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Lions win (67.6%)

Lions vs 49ers Point Spread

The Lions are 3.5-point favorites against the 49ers. The Lions are -102 to cover the spread, while the 49ers are -120 to cover as a 3.5-point underdog.

Lions vs 49ers Over/Under

Lions versus 49ers on Dec. 30 has an over/under of 50.5 points, with the over -105 and the under -115.

Lions vs 49ers Moneyline

The Lions vs 49ers moneyline has the Lions as a -188 favorite, while the 49ers are a +158 underdog at home.

Lions vs 49ers Betting Trends

• Detroit has 10 wins in 15 games against the spread this year.
• The Lions' ATS record as 3.5-point favorites or more is 7-4.
• Out of 15 Lions games so far this season, nine have gone over the total.
• The 49ers have beaten the spread five times in 15 games.
• San Francisco doesn't have a win ATS (0-2) as a 3.5-point underdog or greater this season.
• There have been nine 49ers games (out of 15) that went over the total this season.

Lions vs 49ers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: DET: (-188) | SF: (+158)
• Spread: DET: -3.5 (-102) | SF: +3.5 (-120)
• Total: 50.5 -- Over: (-105) | Under: (-115)

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