Kentucky vs Vanderbilt College Basketball Prediction, Odds, Picks, Best Bets for Feb. 28

SEC play on Saturday will see the the Kentucky Wildcats (18-10, 9-6 SEC) host the No. 25 Vanderbilt Commodores (22-6, 9-6 SEC) at Rupp Arena, beginning at 2 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Kentucky vs. Vanderbilt Game Info and Odds

• Game day: Saturday, February 28, 2026
• Game time: 2 p.m. ET
• TV channel: ESPN
• Location: Lexington, Kentucky
• Arena: Rupp Arena

Kentucky vs. Vanderbilt Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Kentucky win (53.6%)

Before making an informed wager on Kentucky-Vanderbilt outing (in which Kentucky is a 1.5-point favorite and the total has been set at 154.5 points), here are some betting insights and trends for Saturday's game.

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Kentucky vs. Vanderbilt: ATS Betting Stats and Trends

• Kentucky has compiled a 14-14-0 ATS record so far this year.
• Vanderbilt has won 15 games against the spread this season, while failing to cover 13 times.
• When the spread is set as 1.5 or more this season, Kentucky (9-10) covers a lower percentage of those games when it is the favorite (47.4%) than Vanderbilt (1-1) does as the underdog (50%).
• At home, the Wildcats own a worse record against the spread (8-8-0) compared to their ATS record in away games (5-4-0).
• In 2025-26 against the spread, the Commodores have a lower winning percentage at home (.500, 8-8-0 record) than on the road (.556, 5-4-0).
• Kentucky has eight wins against the spread in 15 conference games this year.
• Vanderbilt is 7-8-0 against the spread in SEC play this year.

Kentucky vs. Vanderbilt: Moneyline Betting Stats

• Kentucky has come away with nine wins in the 13 contests it has been listed as the moneyline favorite in this season.
• This season, the Wildcats have been victorious eight times in 12 chances when named as a favorite of at least -120 or shorter on the moneyline.
• Vanderbilt has put together a 1-2 record in games it was the underdog on the moneyline (winning 33.3% of those games).
• The Commodores have played as a moneyline underdog of +100 or longer in just one game this season, which they won.
• The moneyline set for this matchup implies Kentucky has a 54.5% chance of walking away with the win.

Kentucky vs. Vanderbilt Head-to-Head Comparison

• Last year, Kentucky was seventh-best in college basketball offensively (84.4 points scored per game) and ranked 315th defensively (77.2 points allowed).
• Kentucky was 63rd in college basketball in rebounds per game (34.1) and 239th in rebounds conceded (32.1) last year.
• Last season Kentucky was 17th-best in college basketball in assists with 16.9 per game.
• Last season, Kentucky was 108th in college basketball in turnovers committed (10.4 per game) and 312th in turnovers forced (9.9).
• Vanderbilt was 55th in the country last year with 78.9 points per game. At the other end, it ranked 249th with 74.3 points allowed per game.
• Vanderbilt grabbed 31.2 boards per game (221st-ranked in college basketball) last year, while allowing 31.9 rebounds per contest (226th-ranked).
• Vanderbilt averaged 13.8 assists per game, which ranked them 158th in the country.
• Vanderbilt was 40th in the nation with 9.6 turnovers per game last year. Meanwhile, it ranked 40th with 13.4 forced turnovers per game.

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