Kansas State vs Iowa State Prediction, Odds, Picks, Best Bets for Week 1 2025

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The Kansas State Wildcats versus the Iowa State Cyclones is on the college football schedule for Saturday.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA football odds and spreads you need to know.

Kansas State vs Iowa State Odds & Spread

All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
Moneyline: Kansas State: (-160) | Iowa State: (+132)
Spread: Kansas State: -3.5 (-104) | Iowa State: +3.5 (-118)
Total: 50.5 -- Over: (-115) | Under: (-105)

Kansas State was 4-9-0 against the spread last season.
As 3.5-point or greater favorites, Kansas State went 3-8 against the spread last season.
Kansas State had seven of its 13 games hit the over last year.
Iowa State beat the spread eight times in 13 games last season.
Iowa State went unbeaten ATS (1-0) as underdogs of 3.5 points or greater last year.
Last season, eight of Iowa State's 13 games went over the point total.

All college football win probability predictions and picks are according to numberFire.
Prediction: Wildcats win (58.9%)

Kansas State is favored by 3.5 points over Iowa State. Kansas State is -104 to cover the spread, with Iowa State being -118.

The over/under for Kansas State-Iowa State on Aug. 23 is 50.5. The over is -115, and the under is -105.

Kansas State is the favorite, -160 on the moneyline, while Iowa State is a +132 underdog.

The Wildcats' average implied point total last season was 4.5 more points than their implied total in Saturday's game (31.5 implied points on average compared to 27 implied points in this game).
The 29.0-point average implied total last season for the Cyclones is 5.0 more points than the team's 24-point implied total in this matchup.

Check out even more in-depth Kansas State vs. Iowa State analysis on FanDuel Research.

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