Iowa State vs Oklahoma State Basketball Prediction, Odds, Picks, Best Bets for February 25

Big 12 action features the No. 9 Iowa State Cyclones (21-6, 11-5 Big 12) on the road against the Oklahoma State Cowboys (13-14, 5-11 Big 12) on Tuesday, February 25, 2025 at 8:00 PM ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Iowa State vs. Oklahoma State Game Info and Odds

• Game day: Tuesday, February 25, 2025
• Game time: 8:00 PM ET
• TV channel: ESPN+
• Location: Stillwater, Oklahoma
• Arena: Gallagher-Iba Arena

Iowa State vs. Oklahoma State Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Iowa State win (83.3%)

Here's a look at some betting trends and insights for Iowa State (-10.5) versus Oklahoma State on Tuesday. The total has been set at 149.5 points for this game.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Iowa State vs. Oklahoma State: ATS Betting Stats and Trends

• Iowa State has won 16 games against the spread this season, while failing to cover 11 times.
• Oklahoma State has won 11 games against the spread this season, while failing to cover 16 times.
• Iowa State (7-8) covers a higher percentage of games when it is favored by 10.5 points or more this season (46.7%) than Oklahoma State (2-3) does as a 10.5+-point underdog (40%).
• The Cyclones have done a better job covering the spread in road games (6-3-0) than they have at home (8-7-0).
• This year, the Cowboys are 5-8-0 at home against the spread (.385 winning percentage). On the road, they are 5-5-0 ATS (.500).
• Iowa State's record against the spread in conference action is 11-6-0.
• Oklahoma State has eight wins against the spread in 16 Big 12 games this year.

Iowa State vs. Oklahoma State: Moneyline Betting Stats

• Iowa State has come away with 15 wins in the 17 contests it has been listed as the moneyline favorite in this season.
• This year, the Cyclones have won seven of eight games when listed as at least -599 or better on the moneyline.
• Oklahoma State has won one of the 15 games it was the underdog on the moneyline this season (6.7%).
• The Cowboys have played in five games as a moneyline underdog with odds of +430 or longer without earning a win.
• Iowa State has an implied victory probability of 85.7% according to the moneyline set for this matchup.

Iowa State vs. Oklahoma State Head-to-Head Comparison

• Iowa State has a +366 scoring differential, topping opponents by 13.5 points per game. It is putting up 80.5 points per game to rank 40th in college basketball and is allowing 67 per contest to rank 51st in college basketball.
• Curtis Jones' team-leading 17.2 points per game ranks 105th in the nation.
• Oklahoma State puts up 73 points per game (214th in college basketball) while giving up 76.7 per contest (308th in college basketball). It has a -100 scoring differential and has been outscored by 3.7 points per game.
• Bryce Thompson's 12.5 points per game leads Oklahoma State and ranks 597th in college basketball.
• The Cyclones win the rebound battle by 5.5 boards on average. They collect 33.4 rebounds per game, which ranks 94th in college basketball, while their opponents pull down 27.9 per outing.
• Joshua Jefferson averages 7.7 rebounds per game (ranking 84th in college basketball) to lead the Cyclones.
• The Cowboys rank 246th in college basketball at 31 rebounds per game. That's similar to the 30.4 their opponents average.
• Abou Ousmane averages 5.3 rebounds per game (502nd in college basketball) to lead the Cowboys.
• Iowa State averages 102.8 points per 100 possessions on offense (36th in college basketball), and allows 85.5 points per 100 possessions (23rd in college basketball).
• The Cowboys record 92.1 points per 100 possessions (274th in college basketball), while allowing 96.8 points per 100 possessions (279th in college basketball).

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!