Iowa State vs BYU Basketball Prediction, Odds, Picks, Best Bets for Big 12 Tournament

The No. 5 seed Iowa State Cyclones (24-8, 13-7 Big 12) will hit the court in the Big 12 tournament against the No. 4 seed BYU Cougars (23-8, 14-6 Big 12), Thursday at 12:30 p.m. ET live on ESPN2.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Iowa State vs. BYU Game Info and Odds

• Game day: Thursday, March 13, 2025
• Game time: 12:30 p.m. ET
• TV channel: ESPN2
• Location: Kansas City, Missouri
• Arena: T-Mobile Center

Iowa State vs. BYU Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Iowa State win (61.1%)

Before making a wager on Thursday's Iowa State-BYU spread (Iowa State -3.5) or over/under (146.5 points), take a look at the betting trends and insights below.

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Iowa State vs. BYU: ATS Betting Stats and Trends

• Iowa State has put together a 19-13-0 record against the spread this season.
• BYU has won 18 games against the spread this season, while failing to cover 12 times.
• As a 3.5-point underdog or more in 2024-25, BYU is 2-1 against the spread compared to the 16-11 ATS record Iowa State puts up as a 3.5-point favorite.
• The Cyclones have done a better job covering the spread on the road (7-4-0) than they have in home games (9-8-0).
• Against the spread, the Cougars have performed better at home (10-6-0) than away (6-5-0).
• Iowa State has beaten the spread 14 times in 22 conference games.
• BYU is 13-7-0 against the spread in Big 12 play this year.

Iowa State vs. BYU: Moneyline Betting Stats

• Iowa State has come away with 18 wins in the 22 contests it has been listed as the moneyline favorite in this season.
• This season, the Cyclones have come away with a win 18 times in 22 chances when named as a favorite of at least -176 or better on the moneyline.
• BYU has been the moneyline underdog six total times this season. BYU has gone 4-2 in those games.
• In games they have played as a moneyline underdog with odds of +146 or longer, the Cougars have a 2-1 record (winning 66.7% of their games).
• Oddsmakers have implied with the moneyline set for this matchup that Iowa State has a 63.8% chance of pulling out a win.

Iowa State vs. BYU Head-to-Head Comparison

• Iowa State has a +410 scoring differential, topping opponents by 12.8 points per game. It is putting up 80 points per game to rank 41st in college basketball and is giving up 67.2 per outing to rank 49th in college basketball.
• Curtis Jones' team-leading 16.7 points per game ranks 137th in the nation.
• BYU's +349 scoring differential (outscoring opponents by 11.3 points per game) is a result of putting up 81.4 points per game (28th in college basketball) while allowing 70.1 per contest (119th in college basketball).
• Richie Saunders' 16 points per game paces BYU and ranks 187th in the country.
• The Cyclones rank 125th in the country at 32.9 rebounds per game. That's 4.4 more than the 28.5 their opponents average.
• Joshua Jefferson averages 7.5 rebounds per game (ranking 108th in college basketball) to lead the Cyclones.
• The 33.6 rebounds per game the Cougars accumulate rank 82nd in the nation, 6.2 more than the 27.4 their opponents record.
• Keba Keita is 84th in the nation with 7.7 rebounds per game, leading the Cougars.
• Iowa State's 101.7 points per 100 possessions on offense rank 50th in college basketball, and the 85.4 points it allows per 100 possessions rank 19th in college basketball.
• The Cougars' 105.1 points per 100 possessions on offense rank 17th in college basketball, and the 90.6 points they allow per 100 possessions rank 104th in college basketball.

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