Iowa State vs BYU Basketball Prediction, Odds, Picks, Best Bets for March 4

The BYU Cougars (21-8, 12-6 Big 12) will try to build on a six-game winning streak when they visit the Iowa State Cyclones (22-7, 12-6 Big 12) on March 4, 2025 at James H. Hilton Coliseum. The contest airs on ESPN2.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Iowa State vs. BYU Game Info and Odds

• Game day: Tuesday, March 4, 2025
• Game time: 9 p.m. ET
• TV channel: ESPN2
• Location: Ames, Iowa
• Arena: James H. Hilton Coliseum

Iowa State vs. BYU Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Iowa State win (76.4%)

Before you wager on Tuesday's Iowa State-BYU spread (Iowa State -9.5) or over/under (149.5 points), check out the betting insights and trends below.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Iowa State vs. BYU: ATS Betting Stats and Trends

• Iowa State has compiled a 17-12-0 ATS record so far this year.
• BYU has covered 17 times in 28 matchups with a spread this year.
• Iowa State covers the spread when it is a 9.5-point favorite or more 47.1% of the time. That's more often than BYU covers as an underdog of 9.5 or more (never covered this season).
• When playing at home, the Cyclones have a worse record against the spread (9-7-0) compared to their ATS record on the road (6-4-0).
• Against the spread, the Cougars have performed better at home (10-5-0) than on the road (5-5-0).
• Iowa State's record against the spread in conference games is 12-7-0.
• BYU has covered the spread 12 times in 18 Big 12 games.

Iowa State vs. BYU: Moneyline Betting Stats

• Iowa State has been chosen as the moneyline favorite in 19 games this year and has walked away with the win 16 times (84.2%) in those games.
• The Cyclones have a win-loss record of 10-2 when favored by -429 or better by bookmakers this year.
• BYU is 3-2 in games it was listed as the moneyline underdog (winning 60% of those games).
• The Cougars have played as a moneyline underdog of +330 or longer in just one game this season, which they lost.
• Iowa State has an implied victory probability of 81.1% according to the moneyline set by sportsbooks for this matchup.

Iowa State vs. BYU Head-to-Head Comparison

• Iowa State's +377 scoring differential (outscoring opponents by 13 points per game) is a result of scoring 80.2 points per game (43rd in college basketball) while allowing 67.2 per contest (48th in college basketball).
• Curtis Jones' 16.8 points per game lead Iowa State and rank 128th in the nation.
• BYU is outscoring opponents by 11.6 points per game, with a +335 scoring differential overall. It puts up 81 points per game (32nd in college basketball) and allows 69.4 per outing (102nd in college basketball).
• Richie Saunders' team-leading 15.8 points per game rank him 194th in college basketball.
• The 33.2 rebounds per game the Cyclones average rank 110th in college basketball, and are 5.1 more than the 28.1 their opponents pull down per outing.
• Joshua Jefferson's 7.6 rebounds per game lead the Cyclones and rank 95th in college basketball play.
• The Cougars grab 33.3 rebounds per game (94th in college basketball) while conceding 26.9 per contest to opponents. They outrebound opponents by 6.4 boards per game.
• Keba Keita leads the team with 7.5 rebounds per game (106th in college basketball).
• Iowa State ranks 43rd in college basketball by averaging 102.2 points per 100 possessions on offense, and defensively is 19th in college basketball, allowing 85.6 points per 100 possessions.
• The Cougars rank 11th in college basketball with 105.9 points scored per 100 possessions, and 117th defensively with 90.8 points conceded per 100 possessions.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!