Indiana vs Nebraska Prediction, Odds, Picks, Best Bets for Week 6 2026

The Indiana Hoosiers are among the college football teams in action on Saturday, versus the Nebraska Cornhuskers.

Before you make your wager on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding today's NCAA football betting odds.

Indiana vs Nebraska Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Indiana: (-315) | Nebraska: (+250)
• Spread: Indiana: -7.5 (-110) | Nebraska: +7.5 (-110)
• Total: 48.5 -- Over: (-108) | Under: (-112)

Indiana vs Nebraska Betting Trends

• Indiana hasn won once against the spread this season.
• Indiana has won once ATS (1-4) as a 7.5-point or higher favorite this season.
• This year, three of Indiana's five games have hit the over.
• Nebraska's record against the spread in 2026 is 4-1-0.
• Nebraska has played five games this season, and three of them have gone over the total.

Indiana vs Nebraska Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Hoosiers win (81.5%)

Indiana vs Nebraska Point Spread

Indiana is favored by 7.5 points versus Nebraska. Indiana is -110 to cover the spread, while Nebraska is -110.

Indiana vs Nebraska Over/Under

The Indiana-Nebraska game on Oct. 10 has been given an over/under of 48.5 points. The over is -108 and the under is -112.

Indiana vs Nebraska Moneyline

Nebraska is the underdog, +250 on the moneyline, while Indiana is a -315 favorite.

Indiana vs. Nebraska Points Insights

Indiana vs. Nebraska Game Info

• Game day: Saturday, October 10, 2026
• Game time: 12 p.m. ET
• TV channel: FOX
• Location: Lincoln, Nebraska
• Stadium: Memorial Stadium (Lincoln, NE)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth Indiana vs. Nebraska analysis on FanDuel Research.