Houston vs Oklahoma State Prediction, Odds, Picks, Best Bets for Week 7 2026

The Houston Cougars will face the Oklahoma State Cowboys in college football action on Saturday.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NCAA football betting insights.

Houston vs Oklahoma State Odds & Spread

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

• All college football odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: Houston: (-188) | Oklahoma State: (+155)
• Spread: Houston: -4.5 (-108) | Oklahoma State: +4.5 (-112)
• Total: 62.5 -- Over: (-110) | Under: (-110)

Houston vs Oklahoma State Betting Trends

• Houston has three wins in six games against the spread this year.
• Houston owns one win ATS (1-3) as a 4.5-point favorite or greater this year.
• Out of six Houston games so far this season, four have gone over the total.
• Oklahoma State's record against the spread in 2026 is 4-1-0.
• Oklahoma State has yet to lose ATS (1-0) as a 4.5-point underdog or more this year.
• Oklahoma State has seen three of its five games hit the over.

Houston vs Oklahoma State Prediction & Pick

All college football win probability predictions and picks are according to numberFire.
Prediction: Cougars win (82.6%)

Houston vs Oklahoma State Point Spread

Oklahoma State is listed as an underdog by 4.5 points (-112 odds), and Houston, the favorite, is -108 to cover.

Houston vs Oklahoma State Over/Under

Houston versus Oklahoma State on Oct. 17 has an over/under of 62.5 points, with the over -110 and the under -110.

Houston vs Oklahoma State Moneyline

Houston is a -188 favorite on the moneyline, while Oklahoma State is a +155 underdog.

Houston vs. Oklahoma State Points Insights

Houston vs. Oklahoma State Game Info

• Game day: Saturday, October 17, 2026
• Game time: 7:30 p.m. ET
• TV channel: FOX
• Location: Houston, Texas
• Stadium: TDECU Stadium

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!

Check out even more in-depth Houston vs. Oklahoma State analysis on FanDuel Research.