Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 8

Odds updated as of 5:19 a.m.

The Cleveland Guardians versus the Chicago White Sox is on the MLB schedule for Friday.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs White Sox Game Info

• Cleveland Guardians (59-55) vs. Chicago White Sox (42-73)
• Date: Friday, August 8, 2025
• Time: 7:40 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and CLEG

Guardians vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-166) | CHW: (+140)
• Spread: CLE: -1.5 (-100) | CHW: +1.5 (-120)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Guardians vs White Sox Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 7-9, 4.44 ERA vs Aaron Civale (White Sox) - 3-6, 3.99 ERA

The Guardians will call on Tanner Bibee (7-9) versus the White Sox and Aaron Civale (3-6). Bibee and his team are 12-9-0 ATS this season when he starts. Bibee's team has won 63.6% of his starts when they are favored on the moneyline (7-4). The White Sox have a 6-8-0 record against the spread in Civale's starts. The White Sox have been the moneyline underdog in 12 of Civale's starts this season, and they went 3-9 in those matchups.

Guardians vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (52.7%)

Guardians vs White Sox Moneyline

• Looking at the moneyline for Guardians-White Sox, Cleveland is the favorite at -166, and Chicago is +140 playing at home.

Guardians vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Guardians. The White Sox are -120 to cover the spread, and the Guardians are -100.

Guardians vs White Sox Over/Under

• The over/under for the Guardians versus White Sox game on Aug. 8 has been set at 8.5, with -110 odds on the over and -110 odds on the under.

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Guardians vs White Sox Betting Trends

• The Guardians have been victorious in 29, or 64.4%, of the 45 contests they have been chosen as favorites in this season.
• This season Cleveland has come away with a win seven times in eight chances when named as a favorite of at least -166 on the moneyline.
• The Guardians' games have gone over the total in 50 of their 111 opportunities.
• The Guardians are 58-53-0 against the spread in their 111 games with a line set by sportsbooks this season.
• The White Sox have put together a 38-69 record in games they were the underdog on the moneyline (winning 35.5% of those games).
• When playing as a moneyline underdog with odds of +140 or longer, Chicago has a record of 18-46 (28.1%).
• The White Sox have played in 110 games with a set over/under, and have combined with their opponents to go over the total 49 times (49-53-8).
• The White Sox have a 61-49-0 record against the spread this season.

Guardians Player Leaders

• Jose Ramirez leads Cleveland with 124 hits and an OBP of .371, plus a team-best slugging percentage of .520. He's batting .296.
• Among all qualified hitters, he is 12th in batting average, his on-base percentage ranks 16th, and he is 13th in slugging.
• Steven Kwan is hitting .284 with 20 doubles, a triple, nine home runs and 40 walks. He's slugging .399 with an on-base percentage of .345.
• Among qualifying hitters, his batting average places him 22nd, his on-base percentage 50th, and his slugging percentage 108th.
• Kwan takes a three-game streak with at least one hit into this matchup. In his last five games he is hitting .227 with an RBI.
• Carlos Santana has collected 84 base hits, an OBP of .318 and a slugging percentage of .338 this season.
• Kyle Manzardo has been key for Cleveland with 74 hits, an OBP of .310 plus a slugging percentage of .460.

White Sox Player Leaders

• Andrew Benintendi is batting .226 with 13 doubles, two triples, 14 home runs and 29 walks. He's slugging .420 with an on-base percentage of .293.
• Luis Robert has a .309 OBP to lead his team. He has a batting average of .226 while slugging .368.
• He is currently 146th in batting average, 113th in on-base percentage and 140th in slugging percentage among all qualifying hitters.
• Lenyn Sosa has accumulated a team-best slugging percentage (.440) while leading the White Sox in hits (97).
• Mike Tauchman has 13 doubles, a triple, eight home runs and 30 walks while batting .279.

Guardians vs White Sox Head to Head

• 7/13/2025: 6-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 6-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 7/11/2025: 5-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 7/11/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/10/2025: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/9/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/8/2025: 1-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 9/11/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/10/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 9/9/2024: 5-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -210, Underdog Moneyline: +176)

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