Guardians vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 13

Odds updated as of 9:12 a.m.
The MLB schedule on Sunday includes the Cleveland Guardians facing the Chicago White Sox.
Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this matchup.
Guardians vs White Sox Game Info
- Cleveland Guardians (45-49) vs. Chicago White Sox (32-64)
- Date: Sunday, July 13, 2025
- Time: 2:10 p.m. ET
- Venue: Rate Field -- Chicago, Illinois
- Coverage: CHSN and CLEG
Guardians vs White Sox Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: CLE: (-136) | CHW: (+116)
- Spread: CLE: -1.5 (+120) | CHW: +1.5 (-144)
- Total: 8.5 -- Over: (-112) | Under: (-108)
Guardians vs White Sox Probable Starting Pitchers
Probable Pitchers: Joey Cantillo (Guardians) - 1-0, 3.79 ERA vs Aaron Civale (White Sox) - 1-6, 5.17 ERA
The Guardians will give the nod to Joey Cantillo (1-0, 3.79 ERA), who is eyeing win No. 2 on the season, and the White Sox will turn to Aaron Civale (1-6, 5.17 ERA). Cantillo has a record of 2-0-0 ATS in two starts with a spread this season. Cantillo has yet to start a game this season when his team was the moneyline favorite. The White Sox have gone 3-7-0 ATS in Civale's 10 starts that had a set spread. The White Sox have a 1-7 record in Civale's eight starts this season when they were the moneyline underdog.
Guardians vs White Sox Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (52.7%)
Guardians vs White Sox Moneyline
- Chicago is the underdog, +116 on the moneyline, while Cleveland is a -136 favorite despite being on the road.
Guardians vs White Sox Spread
- The White Sox are +1.5 on the run line against the Guardians. The White Sox are -144 to cover, and the Guardians are +120.
Guardians vs White Sox Over/Under
- The over/under for the Guardians versus White Sox game on July 13 has been set at 8.5, with -112 odds on the over and -108 odds on the under.
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Guardians vs White Sox Betting Trends
- The Guardians have been favorites in 32 games this season and have come away with the win 19 times (59.4%) in those contests.
- Cleveland has a record of 7-4 when favored by -136 or more this year.
- The Guardians and their opponents have gone over the total this season in 39 of their 92 opportunities.
- The Guardians have an against the spread mark of 47-45-0 in 92 games with a line this season.
- The White Sox have won 29 of the 90 games they were listed as the moneyline underdog this season (32.2%).
- In games it has played as a moneyline underdog with odds of +116 or longer, Chicago has a 25-53 record (winning only 32.1% of its games).
- The White Sox have combined with opponents to go over the total 39 times this season for a 39-49-5 record against the over/under.
- The White Sox have covered 52.7% of their games this season, going 49-44-0 ATS.
Guardians Player Leaders
- Jose Ramirez leads Cleveland in OBP (.367) and total hits (102) this season. He's batting .297 batting average while slugging .510.
- Among qualified hitters in baseball, his batting average ranks ninth, his on-base percentage ranks 26th, and he is 17th in slugging.
- Ramirez will look for his third straight game with a hit in this contest. During his last five outings he is batting .278 with three home runs, five walks and six RBIs.
- Steven Kwan leads Cleveland in slugging percentage (.398) thanks to 27 extra-base hits. He's batting .287 with an on-base percentage of .344.
- His batting average is 23rd among qualified players, his on-base percentage 58th, and his slugging percentage 104th.
- Kwan has picked up a hit in two straight games. During his last five outings he is hitting .136 with a walk and two RBIs.
- Carlos Santana is batting .235 with a .365 slugging percentage and 41 RBI this year.
- Kyle Manzardo has 14 home runs, 34 RBI and a batting average of .217 this season.
- Manzardo has hit safely in two games in a row. During his last five outings he is batting .167 with a home run, three walks and an RBI.
White Sox Player Leaders
- Miguel Vargas has accumulated 73 hits with a .298 on-base percentage, leading the White Sox in both categories. He's batting .218 and slugging .382.
- He ranks 144th in batting average, 131st in on-base percentage and 120th in slugging percentage among all qualifying hitters in the big leagues.
- Andrew Benintendi has 10 doubles, two triples, 10 home runs and 21 walks while batting .224. He's slugging .409 with an on-base percentage of .287.
- Lenyn Sosa has accumulated a slugging percentage of .424, a team-best for the White Sox.
- Chase Meidroth is batting .244 with six doubles, two home runs and 32 walks.
Guardians vs White Sox Head to Head
- 7/12/2025: 6-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
- 7/11/2025: 5-4 CHW (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
- 7/11/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
- 4/10/2025: 6-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
- 4/9/2025: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -168, Underdog Moneyline: +142)
- 4/8/2025: 1-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 7, Favorite Moneyline: -190, Underdog Moneyline: +160)
- 9/11/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -235, Underdog Moneyline: +194)
- 9/10/2024: 5-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -235, Underdog Moneyline: +194)
- 9/9/2024: 5-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -210, Underdog Moneyline: +176)
- 7/4/2024: 8-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -225, Underdog Moneyline: +188)
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