Guardians vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for April 29

Odds updated as of 2:13 a.m.

The Tuesday schedule in MLB includes a matchup between the Cleveland Guardians and the Minnesota Twins.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Guardians vs Twins Game Info

• Cleveland Guardians (15-13) vs. Minnesota Twins (13-16)
• Date: Tuesday, April 29, 2025
• Time: 6:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and MNNT

Guardians vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-152) | MIN: (+128)
• Spread: CLE: -1.5 (+140) | MIN: +1.5 (-170)
• Total: 8 -- Over: (-110) | Under: (-110)

Guardians vs Twins Probable Starting Pitchers

Probable Pitchers: Tanner Bibee (Guardians) - 2-2, 5.19 ERA vs Chris Paddack (Twins) - 0-3, 6.45 ERA

The probable starters are Tanner Bibee (2-2) for the Guardians and Chris Paddack (0-3) for the Twins. Bibee and his team are 3-2-0 ATS this season when he starts. When Bibee starts a game and his team is the favorite on the moneyline, they have a record of 2-1. The Twins have failed to cover all of the five games Paddack started that had a spread set by bookmakers. The Twins were named the moneyline underdog for one Paddack start this season -- they lost.

Guardians vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (53.3%)

Guardians vs Twins Moneyline

• Minnesota is the underdog, +128 on the moneyline, while Cleveland is a -152 favorite at home.

Guardians vs Twins Spread

• The Twins are +1.5 on the spread (-170 to cover), and Cleveland is +140 to cover the runline.

Guardians vs Twins Over/Under

• A total of 8 runs has been set for the Guardians-Twins contest on April 29, with the over available at -110 and the under at -110.

Bet on Cleveland Guardians vs. Minnesota Twins on FanDuel today!

Guardians vs Twins Betting Trends

• The Guardians have been chosen as favorites in 11 games this year and have walked away with the win eight times (72.7%) in those games.
• Cleveland has been a -152 moneyline favorite on three occasions this season and won every time.
• The Guardians and their opponents have gone over the total this season in 16 of their 28 opportunities.
• In 28 games with a line this season, the Guardians have a mark of 12-16-0 against the spread.
• The Twins have put together a 1-6 record in games they were the underdog on the moneyline (winning 14.3% of those games).
• Minnesota has played as a moneyline underdog of +128 or longer in only one game this season, which it lost.
• The Twins have played in 29 games with a set over/under, and have combined with opponents to go over the total 11 times (11-15-3).
• The Twins have collected a 15-14-0 record against the spread this season (covering 51.7% of the time).

Guardians Player Leaders

• Steven Kwan leads Cleveland with an OBP of .395, plus a team-best slugging percentage of .500. He's batting .345 on the season.
• Among qualified hitters in MLB, he is sixth in batting average, 17th in on-base percentage, and 33rd in slugging.
• Kwan has hit safely in 11 straight games. In his last 10 outings he is hitting .410 with four doubles, a home run, three walks and four RBI.
• Jose Ramirez is hitting .265 with four doubles, five home runs and nine walks, while slugging .459 with an on-base percentage of .321.
• He is 58th in batting average, 85th in on-base percentage and 48th in slugging in the majors.
• Ramirez brings a two-game streak with at least one hit into this matchup. During his last five outings he is hitting .278 with a walk and an RBI.
• Kyle Manzardo has 18 hits and is batting .212 this season.
• Manzardo heads into this game with two games in a row with at least one hit. During his last five outings he is batting .211 with a double, a home run, a walk and two RBI.
• Gabriel Arias has been key for Cleveland with 23 hits, an OBP of .315 plus a slugging percentage of .482.
• Arias has safely hit in four straight games. In his last five games he is hitting .250 with three doubles and an RBI.

Twins Player Leaders

• Byron Keiron Buxton has accumulated 25 hits with a .500 slugging percentage, both team-high numbers for the Twins. He's batting .245 and with an on-base percentage of .275.
• Including all the qualified hitters in MLB, his batting average ranks 83rd, his on-base percentage ranks 129th, and he is 33rd in slugging.
• Buxton hopes to build on a three-game hitting streak in this matchup. During his last five outings he is batting .300 with a triple, two home runs, a walk and seven RBI.
• Ty France has a .330 on-base percentage while slugging .366. Both lead his team. He has a batting average of .248.
• His batting average ranks 75th among all qualified players, his on-base percentage is 71st, and he is 109th in slugging.
• Trevor Larnach is batting .232 with two doubles, four home runs and 13 walks.
• Ryan Jeffers is batting .257 with seven doubles, a home run and nine walks.

Guardians vs Twins Head to Head

• 4/28/2025: 11-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/19/2024: 3-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 9/18/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/17/2024: 4-1 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/16/2024: 4-3 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 8/11/2024: 5-3 CLE (Favorite: Twins, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 6-3 MIN (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/9/2024: 4-2 MIN (Favorite: Twins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 5/19/2024: 5-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/18/2024: 11-4 CLE (Favorite: Twins, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)

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