Guardians vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 8

Odds updated as of 5:12 p.m.

The MLB's Monday slate includes the Cleveland Guardians facing the Kansas City Royals.

We've got you covered, in terms of the most important information regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Royals Game Info

• Cleveland Guardians (72-70) vs. Kansas City Royals (73-70)
• Date: Monday, September 8, 2025
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and FDSKC

Guardians vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-116) | KC: (-102)
• Spread: CLE: +1.5 (-192) | KC: -1.5 (+158)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Guardians vs Royals Probable Starting Pitchers

Probable Pitchers: Slade Cecconi (Guardians) - 5-6, 4.78 ERA vs Ryan Bergert (Royals) - 2-1, 2.61 ERA

This contest's pitching matchup is set, as the Guardians will send Slade Cecconi (5-6) to the mound, while Ryan Bergert (2-1) will get the nod for the Royals. Cecconi and his team are 11-7-0 ATS this season when he starts. Cecconi's team has won 57.1% of his starts when they are favored on the moneyline (4-3). The Royals have an 8-5-0 record against the spread in Bergert's starts. The Royals have been the underdog on the moneyline in nine of Bergert's starts this season, and they went 5-4 in those matchups.

Guardians vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Royals win (53.7%)

Guardians vs Royals Moneyline

• The moneyline numbers for Guardians vs. Royals reveal Cleveland as the favorite (-116) and Kansas City as the underdog (-102) on the road.

Guardians vs Royals Spread

• The Royals are 1.5-run favorites against the spread for this matchup with the Guardians. The Royals are +158 to cover, while the Guardians are -192 to cover as a 1.5-run underdog on the runline.

Guardians vs Royals Over/Under

• An over/under of 7.5 has been set for Guardians-Royals on Sept. 8, with the over being -115 and the under -105.

Bet on Cleveland Guardians vs. Kansas City Royals on FanDuel today!

Guardians vs Royals Betting Trends

• The Guardians have won in 34, or 61.8%, of the 55 contests they have been named as odds-on favorites in this year.
• This season Cleveland has come away with a win 31 times in 50 chances when named as a favorite of at least -116 on the moneyline.
• The Guardians and their opponents have gone over the total this season in 62 of their 139 opportunities.
• The Guardians are 73-66-0 against the spread in their 139 games that had a posted line this season.
• The Royals have won 37 of the 79 games they were the moneyline underdog this season (46.8%).
• In games it has played as a moneyline underdog with odds of -102 or longer, Kansas City has a record of 28-40 (41.2%).
• The Royals have had an over/under set by bookmakers 141 times, and have combined with opponents to go over the total in 59 of those games (59-80-2).
• The Royals are 70-71-0 against the spread this season.

Guardians Player Leaders

• Jose Ramirez leads Cleveland with 147 hits and an OBP of .357 this season. He has a .283 batting average and a slugging percentage of .503.
• He ranks 21st in batting average, 27th in on-base percentage, and 18th in slugging among qualified hitters in the majors.
• Ramirez will look for his fifth straight game with a hit in this matchup. In his last five games he is hitting .368 with two doubles, a triple, a home run, a walk and six RBIs.
• Steven Kwan has an OPS of .713, fueled by an OBP of .333 and a team-best slugging percentage of .380 this season. He's batting .275.
• He is 32nd in batting average, 68th in on-base percentage and 129th in slugging in the majors.
• Kwan has picked up a hit in three games in a row. During his last five outings he is batting .381 with a double, three walks and four RBIs.
• Kyle Manzardo is batting .234 with a .465 slugging percentage and 63 RBI this year.
• Angel Martinez has been key for Cleveland with 91 hits, an OBP of .265 plus a slugging percentage of .360.

Royals Player Leaders

• Bobby Witt Jr. has accumulated 160 hits with a .503 slugging percentage, both team-best marks for the Royals. He's batting .294 and with an on-base percentage of .352.
• Including all the qualified hitters in the majors, he is 10th in batting average, 36th in on-base percentage and 18th in slugging percentage.
• Maikel Garcia leads his team with a .358 on-base percentage. He has a batting average of .294 while slugging .471.
• His batting average ranks 10th among all qualified players, his on-base percentage is 26th, and he is 41st in slugging.
• Vinnie Pasquantino is batting .262 with 24 doubles, a triple, 29 home runs and 44 walks.
• Salvador Perez is hitting .238 with 33 doubles, 25 home runs and 23 walks.

Guardians vs Royals Head to Head

• 7/27/2025: 4-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/26/2025: 6-4 CLE (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 7/26/2025: 5-3 KC (Favorite: Royals, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/13/2025: 4-2 KC (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 4/12/2025: 6-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/11/2025: 7-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 3/30/2025: 6-2 CLE (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 3/29/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 3/27/2025: 7-4 CLE (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 9/4/2024: 4-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)

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