Guardians vs Royals Prediction, Odds, Moneyline, Spread & Over/Under for April 12

Odds updated as of 5:12 p.m.

The Cleveland Guardians are among the MLB squads in action on Saturday, versus the Kansas City Royals.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Royals Game Info

• Cleveland Guardians (7-6) vs. Kansas City Royals (7-7)
• Date: Saturday, April 12, 2025
• Time: 6:10 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and FDSKC

Guardians vs Royals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-134) | KC: (+114)
• Spread: CLE: -1.5 (+152) | KC: +1.5 (-184)
• Total: 7.5 -- Over: (-122) | Under: (-100)

Guardians vs Royals Probable Starting Pitchers

Probable Pitchers: Luis Ortiz (Guardians) - 0-2, 8.44 ERA vs Michael Lorenzen (Royals) - 1-1, 3.18 ERA

The Guardians will give the nod to Luis Ortiz (0-2) against the Royals and Michael Lorenzen (1-1). Ortiz has a record of 0-2-0 ATS in two starts with a spread this season. Ortiz's team lost his only start as a favorite this season. Lorenzen has started two games with set spreads, and the Royals went 1-1-0. The Royals were named the moneyline underdog for one Lorenzen start this season -- they lost.

Guardians vs Royals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (55.5%)

Guardians vs Royals Moneyline

• Cleveland is a -134 favorite on the moneyline, while Kansas City is a +114 underdog on the road.

Guardians vs Royals Spread

• The Guardians are hosting the Royals and are favored by 1.5 runs on the spread. The Guardians are +152 to cover the runline, with the Royals being -184.

Guardians vs Royals Over/Under

• The over/under for the Guardians versus Royals contest on April 12 has been set at 7.5, with -122 odds on the over and -100 odds on the under.

Bet on Cleveland Guardians vs. Kansas City Royals on FanDuel today!

Guardians vs Royals Betting Trends

• The Guardians have come away with five wins in the seven contests they have been listed as the favorites in this season.
• Cleveland has a record of 3-1 in contests when oddsmakers favor them by -134 or more on the moneyline.
• The Guardians and their opponents have gone over in six of their 13 games with a total set by sportsbooks this season.
• The Guardians have posted a record of 5-8-0 against the spread this season.
• The Royals have been the moneyline underdog six total times this season. They've gone 2-4 in those games.
• Kansas City has yet to play a game with moneyline odds of +114 or longer.
• The Royals have played in 14 games with a set over/under, and have combined with their opponents to go over the total six times (6-8-0).
• The Royals have a 6-8-0 record ATS this season (covering 42.9% of the time).

Guardians Player Leaders

• Steven Kwan leads Cleveland with an OBP of .400, plus a team-best slugging percentage of .480. He's batting .340 on the season.
• Among qualifying batters in baseball, his batting average ranks 12th, his on-base percentage ranks 27th, and he is 52nd in slugging.
• Kwan hopes to build on a two-game hitting streak in this matchup. In his last five games he is batting .300 with a home run, a walk and five RBI.
• Kyle Manzardo is hitting .209 with a double, a triple, four home runs and eight walks, while slugging .558 with an on-base percentage of .333.
• Among qualified hitters, his batting average places him 119th, his on-base percentage 76th, and his slugging percentage 27th.
• Jose Ramirez leads Cleveland with 10 hits. He is batting .244 this season and six of his hits have gone for extra bases.
• Carlos Santana is batting .271 with a .357 OBP and five RBI for Cleveland this season.

Royals Player Leaders

• Bobby Witt Jr. has accumulated an on-base percentage of .393 and a slugging percentage of .481. Both lead the Royals. He's batting .308.
• Including all qualifying hitters in the big leagues, his batting average places him 32nd, his on-base percentage is 34th, and he is 51st in slugging.
• Witt brings a four-game hitting streak into this matchup. During his last five outings he is hitting .400 with three doubles, four walks and two RBI.
• Maikel Garcia has collected 12 hits to pace his team. He has a batting average of .279 while slugging .488 with an on-base percentage of .311.
• Including all qualifying hitters, his batting average puts him 50th, his on-base percentage is 99th, and he is 46th in slugging.
• Vinnie Pasquantino is batting .167 with two doubles, a triple, a home run and four walks.
• Jonathan India is hitting .216 with three doubles and eight walks.

Guardians vs Royals Head to Head

• 4/11/2025: 7-0 CLE (Favorite: Guardians, Spread: -1.5, Total: 6.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 3/30/2025: 6-2 CLE (Favorite: Royals, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 3/29/2025: 4-3 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 3/27/2025: 7-4 CLE (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 9/4/2024: 4-1 KC (Favorite: Royals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/3/2024: 7-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 9/2/2024: 4-2 CLE (Favorite: Royals, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/28/2024: 7-5 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 8/27/2024: 6-1 KC (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/26/2024: 9-4 KC (Favorite: Guardians, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)

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