Guardians vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 27

Odds updated as of 4:18 a.m.

In MLB action on Sunday, the Cleveland Guardians play the Boston Red Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this game.

Guardians vs Red Sox Game Info

• Cleveland Guardians (15-11) vs. Boston Red Sox (15-14)
• Date: Sunday, April 27, 2025
• Time: 1:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CLEG and NESN

Guardians vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-110) | BOS: (-106)
• Spread: CLE: +1.5 (-194) | BOS: -1.5 (+160)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Guardians vs Red Sox Probable Starting Pitchers

Probable Pitchers: Logan Allen (Guardians) - 1-1, 2.11 ERA vs Brayan Bello (Red Sox) - 1-0, 1.80 ERA

The probable pitchers are Logan Allen (1-1) for the Guardians and Brayan Bello (1-0) for the Red Sox. Allen and his team have a record of 1-3-0 against the spread when he starts. Allen's team won his only start as a favorite this season. Bello has started only one game with a set spread, which the Red Sox covered. The Red Sox have not been the underdog on the moneyline when Bello starts this season.

Guardians vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (50.8%)

Guardians vs Red Sox Moneyline

• Looking at the moneyline for Red Sox-Guardians, Boston is the underdog at -106, and Cleveland is -110 playing at home.

Guardians vs Red Sox Spread

• The Red Sox are 1.5-run favorites against the spread for this matchup with the Guardians. The Red Sox are +160 to cover, while the Guardians are -194 to cover as a 1.5-run underdog on the runline.

Guardians vs Red Sox Over/Under

• An over/under of 7.5 has been set for Guardians-Red Sox on April 27, with the over being -115 and the under -105.

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Guardians vs Red Sox Betting Trends

• The Guardians have come away with eight wins in the 10 contests they have been listed as the favorites in this season.
• This year Cleveland has won eight of 10 games when listed as at least -110 on the moneyline.
• The Guardians and their opponents have gone over the total this season in 14 of their 26 opportunities.
• The Guardians are 12-14-0 against the spread in their 26 games that had a posted line this season.
• The Red Sox have been the underdog on the moneyline seven total times this season. They've finished 3-4 in those games.
• Boston has a 3-4 record (winning 42.9% of its games) when playing as a moneyline underdog of -106 or longer.
• In the 29 games oddsmakers have set an over/under for the Red Sox, they have combined with opponents to go over the total 13 times (13-14-2).
• The Red Sox are 14-15-0 ATS this season.

Guardians Player Leaders

• Steven Kwan has an OPS of .907, fueled by an OBP of .402 to go with a slugging percentage of .505. He has a .350 batting average, as well.
• Among the qualified hitters in MLB, his batting average ranks fourth, his on-base percentage ranks 14th, and he is 32nd in slugging.
• Kwan will look for his 10th straight game with a hit in this matchup. During his last 10 games he is batting .375 with three doubles, a home run, three walks and four RBI.
• Jose Ramirez has four doubles, five home runs and nine walks. He's batting .264 and slugging .473 with an on-base percentage of .324.
• Among qualified hitters, his batting average ranks him 61st, his on-base percentage 78th, and his slugging percentage 44th.
• Kyle Manzardo has 17 hits and is batting .210 this season.
• Gabriel Arias has been key for Cleveland with 22 hits, an OBP of .318 plus a slugging percentage of .481.
• Arias heads into this game on a three-game hitting streak. In his last five games he is hitting .250 with two doubles and an RBI.

Red Sox Player Leaders

• Alexander David Bregman has put up a team-high OBP (.402) and slugging percentage (.559), and paces the Red Sox in hits (36, while batting .324).
• Including all the qualifying hitters in the majors, his batting average puts him 12th, his on-base percentage ranks 14th, and he is 13th in slugging.
• Bregman brings a seven-game hitting streak into this game. During his last 10 outings he is batting .421 with five doubles, three home runs, eight walks and 10 RBI.
• Wilyer Abreu is batting .273 with six doubles, five home runs and 17 walks. He's slugging .511 with an on-base percentage of .390.
• Including all qualifying hitters, his batting average puts him 52nd, his on-base percentage ranks 21st, and he is 29th in slugging.
• Jarren Duran is hitting .256 with seven doubles, three triples, a home run and nine walks.
• Rafael Devers has eight doubles, three home runs and 23 walks while batting .210.

Guardians vs Red Sox Head to Head

• 4/26/2025: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/26/2025: 5-4 CLE (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/25/2024: 6-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 4/24/2024: 8-0 BOS (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/23/2024: 4-1 CLE (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/18/2024: 5-4 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 4/17/2024: 2-0 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/16/2024: 10-7 CLE (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/15/2024: 6-0 CLE (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/8/2023: 10-3 CLE (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)

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