Guardians vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 18

Odds updated as of 10:12 a.m.

The Cleveland Guardians will face the San Francisco Giants in MLB action on Tuesday.

We've got you covered, in terms of the most important info regarding this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Guardians vs Giants Game Info

• Cleveland Guardians (60-65) vs. San Francisco Giants (51-73)
• Date: Tuesday, August 18, 2026
• Time: 6:40 p.m. ET
• Venue: Progressive Field -- Cleveland, Ohio
• Coverage: CleGuardians.TV and NBCS-BA

Guardians vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CLE: (-184) | SF: (+170)
• Spread: CLE: -1.5 (+114) | SF: +1.5 (-137)
• Total: 8 -- Over: (-115) | Under: (-105)

Guardians vs Giants Probable Starting Pitchers

Probable Pitchers: Foster Griffin (Guardians) - 13-4, 3.25 ERA vs Carson Whisenhunt (Giants) - 3-3, 6.11 ERA

The Guardians will give the nod to Foster Griffin (13-4, 3.25 ERA), who is eyeing win No. 14 on the season, and the Giants will turn to Carson Whisenhunt (3-3, 6.11 ERA). Griffin's team is 15-8-0 against the spread in his starts this season. Griffin's team is 5-1 this season when he starts and they are the moneyline favorite. When Whisenhunt starts, the Giants have gone 4-2-0 against the spread. The Giants have been the underdog on the moneyline in five of Whisenhunt's starts this season, and they went 2-3 in those matchups.

Guardians vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Guardians win (57.2%)

Guardians vs Giants Moneyline

• The moneyline numbers for Guardians vs. Giants reveal Cleveland as the favorite (-184) and San Francisco as the underdog (+170) on the road.

Guardians vs Giants Spread

• The Giants are +1.5 on the spread (-137 to cover), and Cleveland is +114 to cover the runline.

Guardians vs Giants Over/Under

• The over/under for the Guardians versus Giants contest on Aug. 18 has been set at 8, with -115 odds on the over and -105 odds on the under.

Bet on Cleveland Guardians vs. San Francisco Giants on FanDuel today!

Guardians vs Giants Betting Trends

• The Guardians have been chosen as favorites in 67 games this year and have walked away with the win 31 times (46.3%) in those games.
• Cleveland has played as a favorite of -184 or more just one time this year and came away with a win in that game.
• The Guardians and their opponents have gone over in 58 of their 119 games with a total set by sportsbooks this season.
• The Guardians are 56-63-0 against the spread in their 119 games that had a posted line this season.
• The Giants have gone 27-50 in games they were listed as the moneyline underdog (winning 35.1% of those games).
• In games it has played as a moneyline underdog with odds of +170 or longer, San Francisco has gone 2-3 (40%).
• The Giants have played in 121 games with an over/under set, and have combined with their opponents to go over the total 56 times (56-56-9).
• The Giants have gone 55-66-0 against the spread this season.

Guardians Player Leaders

• Chase DeLauter has 115 hits to go with a slugging percentage of .442, both of which are tops among Cleveland hitters this season. He has a .285 batting average and an on-base percentage of .358.
• He ranks 20th in batting average, 37th in on-base percentage, and 56th in slugging among qualified hitters in MLB.
• Jose Ramirez is hitting .236 with 19 doubles, 10 home runs and 54 walks. He's slugging .382 with an on-base percentage of .341.
• Among qualifying batters, his batting average places him 107th, his on-base percentage 59th, and his slugging percentage 114th.
• Ramirez enters this game looking to extend his two-game hit streak. During his last five outings he is batting .200 with a double, five walks and two RBIs.
• Brayan Rocchio is batting .253 with a .376 slugging percentage and 51 RBI this year.
• Steven Kwan leads Cleveland in OBP (.366) this season, fueled by 106 hits.

Giants Player Leaders

• Jung Hoo Lee has racked up an on-base percentage of .328 and a slugging percentage of .432. Both lead the Giants. He's batting .292.
• Including all the qualified hitters in the big leagues, he ranks 12th in batting average, 78th in on-base percentage and 62nd in slugging percentage.
• Rafael Devers is hitting .246 with 30 doubles, a triple, 25 home runs and 52 walks. He's slugging .474 with an on-base percentage of .320.
• Including all qualifying hitters, he is 90th in batting average, 92nd in on-base percentage and 31st in slugging percentage.
• Willy Adames is hitting .224 with 25 doubles, a triple, 19 home runs and 36 walks.
• Bryce Eldridge is hitting .247 with 15 doubles, 13 home runs and 42 walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!