Giants vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for June 29

Odds updated as of 5:12 a.m.

The MLB slate on Sunday includes the San Francisco Giants taking on the Chicago White Sox.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Giants vs White Sox Game Info

• San Francisco Giants (45-38) vs. Chicago White Sox (27-56)
• Date: Sunday, June 29, 2025
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and NBCS-BA

Giants vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-146) | CHW: (+124)
• Spread: SF: -1.5 (+112) | CHW: +1.5 (-134)
• Total: 8.5 -- Over: (-110) | Under: (-110)

Giants vs White Sox Probable Starting Pitchers

Probable Pitchers: Justin Verlander (Giants) - 0-5, 4.67 ERA vs Jonathan Cannon (White Sox) - 2-7, 4.66 ERA

The Giants will look to Justin Verlander (0-5) versus the White Sox and Jonathan Cannon (2-7). Verlander and his team have a record of 3-9-0 against the spread when he starts. When Verlander starts a game and his team is the favorite on the moneyline, they have a record of 3-4. The White Sox have gone 3-7-0 against the spread when Cannon starts. The White Sox have been the moneyline underdog in 10 of Cannon's starts this season, and they went 1-9 in those games.

Giants vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (57.1%)

Giants vs White Sox Moneyline

• The moneyline numbers for Giants vs. White Sox reveal San Francisco as the favorite (-146) and Chicago as the underdog (+124) despite being the home team.

Giants vs White Sox Spread

• The Giants are favored by 1.5 runs on the road versus the White Sox. The Giants are +112 to cover the spread, while the White Sox are -134.

Giants vs White Sox Over/Under

• The over/under for the Giants versus White Sox contest on June 29 has been set at 8.5, with -110 odds on the over and -110 odds on the under.

Bet on San Francisco Giants vs. Chicago White Sox on FanDuel today!

Giants vs White Sox Betting Trends

• The Giants have been favorites in 56 games this season and have come away with the win 31 times (55.4%) in those contests.
• San Francisco has a record of 17-14 when favored by -146 or more this year.
• The Giants and their opponents have gone over in 37 of their 83 games with a total set by sportsbooks this season.
• The Giants are 36-47-0 against the spread in their 83 games with a line set by sportsbooks this season.
• The White Sox have been the underdog on the moneyline 79 total times this season. They've gone 25-54 in those games.
• When playing as a moneyline underdog with odds of +124 or longer, Chicago has a 21-44 record (winning just 32.3% of its games).
• The White Sox have played in 80 games with an over/under set, and have combined with opponents to go over the total 36 times (36-40-4).
• The White Sox have covered 55% of their games this season, going 44-36-0 ATS.

Giants Player Leaders

• Rafael Devers has 84 hits and an OBP of .392, both of which lead San Francisco hitters this season. He has a .267 batting average and a slugging percentage of .492.
• Among all qualifying hitters in MLB, he ranks 61st in batting average, sixth in on-base percentage, and 26th in slugging.
• Jung Hoo Lee is batting .246 with 17 doubles, six triples, six home runs and 29 walks. He's slugging .402 with an on-base percentage of .315.
• He is 107th in batting average, 106th in on-base percentage and 102nd in slugging in the majors.
• Heliot Ramos leads San Francisco in slugging percentage (.463) powered by 30 extra-base hits.
• Wilmer Flores has 11 home runs, 55 RBI and a batting average of .243 this season.

White Sox Player Leaders

• Miguel Vargas has an on-base percentage of .312, a slugging percentage of .415, and has 68 hits, all club-bests for the White Sox (while batting .231).
• Including all the qualifying hitters in the majors, he is 132nd in batting average, 111th in on-base percentage and 90th in slugging percentage.
• Andrew Benintendi is hitting .237 with nine doubles, two triples, 10 home runs and 17 walks. He's slugging .455 with an on-base percentage of .300.
• Chase Meidroth is batting .260 with five doubles, two home runs and 28 walks.
• Luis Robert has eight doubles, eight home runs and 29 walks while batting .185.

Giants vs White Sox Head to Head

• 6/28/2025: 1-0 CHW (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 6/27/2025: 3-1 SF (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 8/21/2024: 6-2 CHW (Favorite: Giants, Spread: -1.5, Total: 6.5, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 8/20/2024: 4-1 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 8/19/2024: 5-3 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
• 4/6/2023: 16-6 SF (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/5/2023: 7-3 CHW (Favorite: White Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 4/3/2023: 12-3 SF (Favorite: White Sox, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/3/2022: 13-4 CHW (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/2/2022: 5-3 CHW (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -148, Underdog Moneyline: +126)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!