Giants vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for March 27

Odds updated as of 3:17 p.m.

On Thursday in MLB, the San Francisco Giants are up against the Cincinnati Reds.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info regarding this matchup.

Giants vs Reds Game Info

• San Francisco Giants (0-0) vs. Cincinnati Reds (0-0)
• Date: Thursday, March 27, 2025
• Time: 4:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: FDSOH and NBCS-BA

Giants vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-110) | CIN: (-106)
• Spread: SF: -1.5 (+146) | CIN: +1.5 (-178)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Giants vs Reds Probable Starting Pitchers

Probable Pitchers: Logan Webb (Giants) - 0-0, 0.00 ERA vs Hunter Greene (Reds) - 0-0, 0.00 ERA

The Giants will call on Logan Webb versus the Reds and Hunter Greene. In 33 games he pitched with a spread last season, Webb and his team finished with a 14-19-0 record ATS. Webb and his team won 52.6% of the games he started as the moneyline favorite last season, with a record of 10-9. Last season Greene and his team had a 13-13-0 record against the spread when he pitched. Greene and his team went 5-6 in games he pitched when they were the underdog on the moneyline a season ago.

Giants vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (53.1%)

Giants vs Reds Moneyline

• San Francisco is a -110 favorite on the moneyline, while Cincinnati is a -106 underdog at home.

Giants vs Reds Spread

• The Reds are hosting the Giants, and are +1.5 on the runline. The Reds are +146 to cover the spread, and the Giants are -178.

Giants vs Reds Over/Under

• The over/under for the Giants versus Reds game on March 27 has been set at 7.5, with -118 odds on the over and -104 odds on the under.

Bet on San Francisco Giants vs. Cincinnati Reds on FanDuel today!

Giants vs Reds Betting Trends

• The Giants were chosen as favorites in 81 games last year and walked away with the win 45 times (55.6%) in those games.
• Last year, San Francisco won 45 of 81 games when listed as at least -110 on the moneyline.
• The Giants and their opponents hit the over in 82 of their 160 games with a total last season.
• The Reds put together a 38-48 record in games last season when they were listed as the moneyline underdog (winning 44.2% of those games).
• Cincinnati went 37-48 when playing as a moneyline underdog with odds of -106 or longer (43.5%).
• The Reds played in 156 games with an over/under set last season, and combined with their opponents to go over the total 72 times (72-77-7).

Giants Player Leaders

• Willy Adames had an OBP of .331 to go with a slugging percentage of .462 last season.
• Matt Chapman slashed .247/.328/.463 and finished with an OPS of .790.
• Heliot Ramos finished last season with 128 hits while batting .269.
• Mike Yastrzemski slashed .231/.302/.437 and finished with an OPS of .739.

Reds Player Leaders

• Elly De La Cruz put up an OBP of .339 and a slugging percentage of .471 while racking up 160 hits last season.
• Spencer Steer hit .225 with 34 doubles, four triples, 20 home runs and 72 walks.
• Gavin Lux had 24 doubles, two triples, 10 home runs and 44 walks while batting .251 last season.
• Jeimer Candelario hit .225 with 23 doubles, two triples, 20 home runs and 27 walks.

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