Giants vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for September 12

Odds updated as of 7:31 PM

On Tuesday in the MLB, the San Francisco Giants are playing the Cleveland Guardians.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Giants vs Guardians Game Info

• San Francisco Giants (74-70) vs. Cleveland Guardians (68-77)
• Date: Tuesday, September 12, 2023
• Time: 9:45 PM ET
• Venue: Oracle Park -- San Francisco, California
• Coverage: MLB Network

Giants vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: SF: (-180) | CLE: (+152)
• Spread: SF: -1.5 (+115) | CLE: +1.5 (-138)
• Total: 8.5 -- Over: (-106) | Under: (-114)

Giants vs Guardians Probable Starting Pitchers

Probable Pitchers: Sean Manaea (Giants) - 5-5, 5.00 ERA vs Cal Quantrill (Guardians) - 2-6, 5.70 ERA

The probable starters are Sean Manaea (5-5) for the Giants and Quantrill (2-6) for the Guardians. When Manaea starts, his team is 1-5-0 against the spread this season. Manaea's team has been upset in each of the three games he's started as the moneyline favorite. The Guardians are 5-10-0 against the spread when Quantrill starts. The Guardians have a 5-4 record in Quantrill's nine starts this season when they were the underdog on the moneyline.

Giants vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (62.2%)

Giants vs Guardians Moneyline

• Cleveland is the underdog, +152 on the moneyline, while San Francisco is a -180 favorite at home.

Giants vs Guardians Spread

• The Giants are hosting the Guardians and are favored by 1.5 runs (+115 to cover) on the runline. Cleveland is -138 to cover.

Giants vs Guardians Over/Under

• Giants versus Guardians, on September 12, has an over/under of 8.5, with the over being -106 and the under -114.

Bet on San Francisco Giants vs. Cleveland Guardians on FanDuel today!

Giants vs Guardians Betting Trends

• The Giants have come away with 41 wins in the 74 contests they have been listed as the favorites in this season.
• San Francisco has a record of 11-5 when favored by -180 or more this year.
• The Giants and their opponents have gone over the total this season in 62 of their 144 opportunities.
• The Giants have an against the spread record of 66-78-0 in 144 games with a line this season.
• The Guardians have put together a 28-42 record in games they were the underdog on the moneyline (winning 40% of those games).
• Cleveland is 2-6 (winning only 25% of its games) when playing as a moneyline underdog of +152 or longer.
• The Guardians have combined with opponents to go over the total 60 times this season for a 60-79-2 record against the over/under.
• The Guardians have covered 51.8% of their games this season, going 73-68-0 ATS.

Giants Player Leaders

• Wilmer Flores is batting .287 with 22 doubles, 22 home runs and 34 walks. He has an on-base percentage of .351 while slugging .529.
• LaMonte Wade Jr leads San Francisco in OBP (.374) this season, fueled by 100 hits. He's batting .258 while slugging .407.
• Among qualifying batters, his batting average places him 81st, his on-base percentage 14th, and his slugging percentage 105th.
• Wade enters this matchup looking to extend his three-game hit streak. During his last five outings he is batting .438 with a home run, two walks and three RBI.
• Thairo Estrada leads San Francisco in slugging percentage (.426) and total hits (116) this season.
• Estrada has logged a hit or more in four straight games. In his last five games he is hitting .261 with a triple, two home runs and four RBI.
• J.D. Davis has 17 home runs, 65 RBI and a batting average of .251 this season.

Guardians Player Leaders

• Jose Ramirez has racked up a team-best OBP (.349), while pacing the Guardians in hits (148). He's batting .273 and slugging.
• Including all qualifying players in the majors, he is 37th in batting average, 37th in on-base percentage and 44th in slugging percentage.
• Steven Kwan's .375 slugging percentage leads his team. He has a batting average of .272 with an on-base percentage of .340.
• His batting average ranks 42nd among all qualified players, his on-base percentage is 45th, and he is 124th in slugging.
• Josh Naylor is batting .310 with 27 doubles, 17 home runs and 27 walks.
• Andres Gimenez has 25 doubles, four triples, 12 home runs and 32 walks while batting .240.

Giants vs. Guardians Head to Head

• 9/11/2023: 5-4 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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