Giants vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for April 1

Odds updated as of 7:11 p.m.

The Houston Astros versus the San Francisco Giants is on the MLB schedule for Tuesday.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this matchup.

Astros vs Giants Game Info

• Houston Astros (2-2) vs. San Francisco Giants (3-1)
• Date: Tuesday, April 1, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-BA+

Astros vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-174) | SF: (+146)
• Spread: HOU: -1.5 (+118) | SF: +1.5 (-142)
• Total: 8.5 -- Over: (+102) | Under: (-124)

Astros vs Giants Probable Starting Pitchers

Probable Pitchers: Hayden Wesneski (Astros) - 0-0, 0.00 ERA vs Logan Webb (Giants) - 0-0, 5.40 ERA

The Astros will look to Hayden Wesneski against the Giants and Logan Webb. In seven games he pitched with a spread last season, Wesneski and his team finished with a 2-5-0 record ATS. Wesneski and his team won 33.3% of the games he started as the moneyline favorite last season, with a record of 1-2. Webb has started only one game with a set spread, which the Giants covered. The Giants have not been a moneyline underdog when Webb starts this season.

Astros vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (51.1%)

Astros vs Giants Moneyline

• Looking at the moneyline for Astros-Giants, Houston is the favorite at -174, and San Francisco is +146 playing on the road.

Astros vs Giants Spread

• The Astros are 1.5-run home favorites on the runline against the Giants. The Astros are +118 to cover, and the Giants are -142.

Astros vs Giants Over/Under

• An over/under of 8.5 has been set for Astros-Giants on April 1, with the over being +102 and the under -124.

Bet on Houston Astros vs. San Francisco Giants on FanDuel today!

Astros vs Giants Betting Trends

• The Astros were favorites in 117 games last season and came away with the win 66 times (56.4%) in those contests.
• Last season Houston came away with a win 26 times in 38 chances when named as a favorite of at least -174 or shorter on the moneyline.
• The Astros and their opponents hit the over in 65 of their 163 games with a total last season.
• The Giants won 32 of the 73 games they were the moneyline underdog last season (43.8%).
• In games it played as a moneyline underdog with odds of +146 or longer last year, San Francisco went 8-9 (47.1%).
• The Giants combined with their opponents to hit the over on the total 82 times last season for an 82-73-5 record against the over/under.

Astros Player Leaders

• Yordan Alvarez had 170 hits and an OBP of .392 last season.
• Jose Altuve had an OPS of .790, fueled by an OBP of .350 and a slugging percentage of .439.
• Last season, Yainer Diaz finished with 16 home runs, 84 RBI and a batting average of .299 last season.
• Isaac Paredes slashed .238/.346/.393 and finished with an OPS of .739.

Giants Player Leaders

• Willy Adames accumulated a .331 on-base percentage and a .462 slugging percentage last season.
• Matt Chapman hit .247 with 39 doubles, two triples, 27 home runs and 64 walks.
• Heliot Ramos had 128 hits and a batting average of .269 a season ago.
• Mike Yastrzemski hit .231 with 16 doubles, nine triples, 18 home runs and 38 walks.

Astros vs Giants Head to Head

• 3/31/2025: 7-2 SF (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/12/2024: 5-3 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/11/2024: 3-1 HOU (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/10/2024: 4-3 SF (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/3/2023: 4-2 SF (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/2/2023: 2-0 SF (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 5/1/2023: 7-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)

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