We get the final game of the regular season on Sunday night between the Buffalo Bills and Miami Dolphins with the winner taking home the AFC East crown. Depending on the outcomes earlier in the day, there's also a slim chance the Bills could miss the playoffs entirely with a loss. According to the NFL odds on FanDuel Sportsbook, Buffalo is a 2.5-point road favorite, and the matchup has a week-high 48.5 over/under.

For those unfamiliar, single-game slates feature five flex spots with identical scoring to the main slate. However, kickers are included in these contests, and there is an "MVP" roster slot. The MVP receives 1.5 times his total fantasy points, making this spot crucial.

FanDuel Research's Brandon Gdula has done a deep dive on single-game strategy, and numberFire has projections if you select the game from the slate tab. It's worth checking out both before making your lineups.

NFL DFS Single-Game Picks

MVP Candidates

The obvious answer at MVP is Josh Allen ($17,000), who leads all positions in FanDuel points per game (24.1) this season. While the dual-threat QB has been erratic at times, the highs have included seven games of 25-plus FanDuel points, including three performances cracking 30 points.

FanDuel Sportsbook's Weekly Specials Betting Odds, the Bills have +1100 odds to be the highest-scoring team on Sunday behind just the Dallas Cowboys (+380). If Buffalo is going to get there, it's almost certainly because of a massive game from Allen.

Miami's Tyreek Hill ($16,000) is back at practice on Friday, so he should be good to go as a potential top play. In 15 games, Hill leads the team in target share (31.9%), air yards share (43.0%), red zone target share (33.8%), and end zone target share (33.3%). He's been a matchup-proof option all year, and his ceiling hasn't been all that different from Allen's, boasting six games with 25-plus FanDuel points. Hill is projected for the second-most points in numberFire's model behind Allen, and the two players figure to be the most popular MVPs.

Tua Tagovailoa ($13,500) ranks third in the projections, but the truth is he's hard to count on to lead the slate in scoring. Over his last eight games, Tua has topped out at 19.2 FanDuel points, and a big game from him is typically dwarfed by an even bigger one from Hill. Still, a QB in a possible shootout will always have some upside, and Tagovailoa has thrown three or more touchdowns on four occasions this season.

James Cook ($12,000) and Stefon Diggs ($12,500) are the other Buffalo players who project well. With Joe Brady calling plays, Cook has averaged 17.3 rushes and 3.7 targets per game, and Brady hasn't been afraid to lean on Cook when he's cooking. Although his red zone rush share (23.9%) remains much lower than we would like, his two best games have come since the change at OC (35.1 and 22.6 FanDuel points). Cook could do damage through the air versus a defense that's 29th in adjusted fantasy points allowed per target to RBs, too.

Diggs' recent performances make him difficult to get behind, and the possibility of cornerback Jalen Ramsey shadowing him further dampens his appeal. That being said, all of this could keep his MVP roster percentage down, and we saw him blow up for big games earlier in the season. Under Brady, Diggs has seen a 28.4% target share, so it's not like he isn't getting looks. He's an intriguing contrarian pick.

Finally, with Raheem Mostert ($14,500) returning to practice on Friday, we could see Miami go back to a split backfield between him and De'Von Achane ($14,000). Mostert tends to be the lead back and primary red-zone threat, while Achane is the pass-catching threat, so game flow could determine how their opportunities shake out.

While the two RBs eat into each other's workload, both have demonstrated multi-touchdown upside that can't be ignored. Buffalo has been a middle-of-the-pack defense against the run, ranking 16th in schedule-adjusted rush D, per numberFire. It's also possible Mostert ultimately remains inactive, which would boost Achane's outlook significantly.

Flex Breakdown

Jaylen Waddle ($11,500) is another injured Dolphins player who got a Friday practice in. If he's active, he should return to a role that's led to a 22.7% target share and 29.5% air yards share this season. He's a solid flex play, but Buffalo's given up the seventh-fewest FanDuel points per game to WRs, so his upside could be limited, particularly coming off injury.

Cedrick Wilson ($8,500) is Miami's No. 3 wideout, so he's the primary beneficiary if Waddle is out. In Week 17, Wilson logged season-highs in snap rate (84.8%) and route rate (87.8%) with Waddle sidelined, though it amounted to just four targets (11.1% share). Despite the lack of production, Wilson is an intriguing value play if Waddle ends up being inactive, and he still holds some fringe appeal as a touchdown-or-bust play if Waddle suits up.

Tight end Durham Smythe ($6,500) is the one other Miami pass-catcher to consider before getting to the true dart throws. Smythe has an 8.2% target share off a 65.0% route rate this season, and he's coming off back-to-back performances with over 50 receiving yards. However, he hasn't scored a touchdown yet in this campaign.

Running back Jeff Wilson ($8,000) should be on the radar if Mostert sits, as he did log 48.5% of the snaps with Mostert out last week, albeit in a blowout loss. He would still be a longshot to crack the optimal lineup, but a best-case scenario could include double-digit opportunities behind Achane.

Hopping over to the Bills, Gabriel Davis ($10,500), Dalton Kincaid ($10,000), and Khalil Shakir ($8,000) are the team's top pass-catchers after Diggs.

Davis is as all-or-nothing as ever. Since Brady took over as OC, Davis has scored 0.0, 19.5, 0.0, 0.0, 21.0, and 3.1 FanDuel points. He'll either single-handedly sink your lineup or vault it up the leaderboards.

Last week, Kincaid bounced back by catching 4-of-7 targets for 87 yards, but he still played just 55.9% of the snaps with Dawson Knox continuing to hurt his playing time. numberFire's model remains bullish, though, projecting Kincaid for 6.2 targets, the third-most on the slate.

Shakir was busy in Week 17, logging a 79.4% snap rate and 74.2% route rate, his highest marks in weeks. As a low-aDOT player, he isn't likely to accumulate a ton of yardage, but the bump in snaps is encouraging for this salary range.

Given that this matchup has a high total and could be a back-and-forth affair, the kickers and defenses are less likely to finish in the perfect lineup. Jason Sanders ($9,000) and Tyler Bass ($9,000) do project well, though, so you could certainly do worse if you need a value play.

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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.