Duke vs Mount St. Mary's Basketball Prediction, Odds, Picks, Best Bets for NCAA Tournament First Round

The No. 1 seed Duke Blue Devils (31-3) will look to defeat the No. 16 seed Mount St. Mary's Mountaineers (23-12) in the first round of the NCAA Tournament on Friday at Lenovo Center. This contest tips off at 2:50 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. Mount St. Mary's Game Info and Odds

• Game day: Friday, March 21, 2025
• Game time: 2:50 p.m. ET
• TV channel: CBS
• Location: Raleigh, North Carolina
• Arena: Lenovo Center

Duke vs. Mount St. Mary's Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Duke win (94.6%)

Before making a wager on Friday's Duke-Mount St. Mary's spread (Duke -32.5) or total (140.5 points), check out the betting trends and insights below.

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Duke vs. Mount St. Mary's: ATS Betting Stats and Trends

• Duke has won 22 games against the spread this season, while failing to cover 12 times.
• Mount St. Mary's has put together a 23-11-0 ATS record so far this year.
• The Blue Devils have done a better job covering the spread when playing on the road (9-2-0) than they have at home (11-6-0).
• This season, the Mountaineers are 8-5-0 at home against the spread (.615 winning percentage). Away, they are 11-6-0 ATS (.647).

Duke vs. Mount St. Mary's: Moneyline Betting Stats

• Duke has been chosen as the moneyline favorite in 32 games this year and has walked away with the win 29 times (90.6%) in those games.
• The Blue Devils have yet to play a game this season with better moneyline odds than -100000.
• Mount St. Mary's has put together a 12-7 record in games it was listed as the moneyline underdog (winning 63.2% of those games).
• The Mountaineers have never played a game this season with moneyline odds of +8000 or longer.
• Duke has an implied victory probability of 99.9% according to the moneyline set by oddsmakers for this matchup.

Duke vs. Mount St. Mary's Head-to-Head Comparison

• Duke outscores opponents by 20.8 points per game (scoring 82.7 per game to rank 15th in college basketball while giving up 61.9 per outing to rank seventh in college basketball) and has a +707 scoring differential overall.
• Cooper Flagg's 18.9 points per game lead Duke and rank 46th in the nation.
• Mount St. Mary's scores 70.7 points per game (264th in college basketball) and allows 69.9 (111th in college basketball) for a +30 scoring differential overall.
• Dola Adebayo's team-leading 13.4 points per game rank him 464th in the nation.
• The Blue Devils win the rebound battle by nine boards on average. They collect 35.9 rebounds per game, which ranks 19th in college basketball, while their opponents grab 26.9 per contest.
• Flagg averages 7.5 rebounds per game (ranking 105th in college basketball) to lead the Blue Devils.
• The 34.3 rebounds per game the Mountaineers accumulate rank 59th in the nation, 4.0 more than the 30.3 their opponents grab.
• Jedy Cordilia is 129th in the country with 7.3 rebounds per game, leading the Mountaineers.
• Duke ranks first in college basketball with 110.1 points scored per 100 possessions, and fourth in college basketball defensively with 82.4 points conceded per 100 possessions.
• The Mountaineers rank 292nd in college basketball with 91.3 points scored per 100 possessions, and 91st defensively with 90.2 points conceded per 100 possessions.

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