Duke vs Florida State Basketball Prediction, Odds, Picks, Best Bets for March 1

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The Duke Blue Devils (25-3, 16-1 ACC) will host the Florida State Seminoles (16-12, 7-10 ACC) after winning 14 straight home games.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Duke vs. Florida State Game Info and Odds

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Duke win (92.5%)

Before you bet on Saturday's Duke-Florida State spread (Duke -23.5) or total (148.5 points), check out the betting insights and trends below.

Duke has won 18 games against the spread this season, while failing to cover 10 times.
Florida State has won 15 games against the spread this year, while failing to cover 13 times.
The Blue Devils own a worse record against the spread when playing at home (9-6-0) than they do in road games (8-2-0).
In 2024-25 against the spread, the Seminoles have a better winning percentage at home (.600, 9-6-0 record) than away (.333, 3-6-0).
Duke has 11 wins against the spread in 17 conference games this season.
Florida State is 7-10-0 against the spread in ACC play this season.

Duke has been chosen as the moneyline favorite in 26 games this year and has walked away with the win 23 times (88.5%) in those games.
The Blue Devils have yet to lose in nine games when named as moneyline favorite of -10000 or better.
Florida State has been the underdog on the moneyline 11 total times this season. Florida State has finished 3-8 in those games.
The Seminoles have not yet played as a moneyline underdog of +2400 or longer.
Bookmakers have implied with the moneyline set for this matchup that Duke has a 99% chance of pulling out a win.

Duke is outscoring opponents by 21.6 points per game with a +604 scoring differential overall. It puts up 82.6 points per game (17th in college basketball) and gives up 61.0 per contest (eighth in college basketball).
Duke's leading scorer, Cooper Flagg, ranks 30th in the nation putting up 19.4 points per game.
Florida State is outscoring opponents by 3.5 points per game, with a +99 scoring differential overall. It puts up 75.8 points per game (126th in college basketball) and gives up 72.3 per contest (197th in college basketball).
Florida State's leading scorer, Jamir Watkins, is 55th in college basketball, scoring 18.4 points per game.
The Blue Devils win the rebound battle by 9.0 boards on average. They collect 35.7 rebounds per game, which ranks 26th in college basketball, while their opponents grab 26.7 per outing.
Flagg averages 7.6 rebounds per game (ranking 96th in college basketball) to lead the Blue Devils.
The 31.3 rebounds per game the Seminoles accumulate rank 223rd in the nation. Their opponents grab 31.4.
Malique Ewin leads the Seminoles with 7.8 rebounds per game (81st in college basketball).
Duke averages 110.8 points per 100 possessions on offense (first in college basketball), and allows 81.8 points per 100 possessions (fourth in college basketball).
The Seminoles average 95.1 points per 100 possessions on offense (194th in college basketball), and allow 90.6 points per 100 possessions (116th in college basketball).

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