Dodgers vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 6

Odds updated as of 3:11 p.m.

The Wednesday schedule in MLB includes a matchup between the Los Angeles Dodgers and the St. Louis Cardinals.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital information regarding this matchup.

Dodgers vs Cardinals Game Info

• Los Angeles Dodgers (66-48) vs. St. Louis Cardinals (57-58)
• Date: Wednesday, August 6, 2025
• Time: 4:10 p.m. ET
• Venue: Dodger Stadium -- Los Angeles, California
• Coverage: MLB Network, SportsNet LA, and FDSMW

Dodgers vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAD: (-184) | STL: (+154)
• Spread: LAD: -1.5 (+104) | STL: +1.5 (-125)
• Total: 9 -- Over: (-114) | Under: (-106)

Dodgers vs Cardinals Probable Starting Pitchers

Probable Pitchers: Shohei Ohtani (Dodgers) - 0-0, 2.40 ERA vs Matthew Liberatore (Cardinals) - 6-9, 3.96 ERA

The Dodgers will look to Shohei Ohtani against the Cardinals and Matthew Liberatore (6-9). Ohtani and his team have a record of 3-4-0 against the spread when he starts. When Ohtani starts a game and his team is the favorite on the moneyline, they have a record of 4-3. When Liberatore starts, the Cardinals are 9-11-0 against the spread. The Cardinals have been the underdog on the moneyline in seven of Liberatore's starts this season, and they went 5-2 in those matchups.

Dodgers vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Dodgers win (62.2%)

Dodgers vs Cardinals Moneyline

• Looking at the moneyline for Cardinals-Dodgers, St. Louis is the underdog at +154, and Los Angeles is -184 playing at home.

Dodgers vs Cardinals Spread

• The Cardinals are +1.5 on the run line against the Dodgers. The Cardinals are -125 to cover, and the Dodgers are +104.

Dodgers vs Cardinals Over/Under

• An over/under of 9 has been set for Dodgers-Cardinals on Aug. 6, with the over being -114 and the under -106.

Bet on Los Angeles Dodgers vs. St. Louis Cardinals on FanDuel today!

Dodgers vs Cardinals Betting Trends

• The Dodgers have come away with 58 wins in the 97 contests they have been listed as the favorites in this season.
• Los Angeles has a record of 30-14 in contests when sportsbooks favor them by -184 or more on the moneyline.
• The Dodgers and their opponents have hit the over in 56 of their 112 games with a total set by oddsmakers this season.
• The Dodgers have an against the spread record of 47-65-0 in 112 games with a line this season.
• The Cardinals have won 29 of the 59 games they were the moneyline underdog this season (49.2%).
• When playing as a moneyline underdog with odds of +154 or longer, St. Louis has a 1-5 record (winning only 16.7% of its games).
• The Cardinals have played in 112 games with a set over/under, and have combined with their opponents to go over the total 57 times (57-50-5).
• The Cardinals have gone 58-54-0 against the spread this season.

Dodgers Player Leaders

• Ohtani leads Los Angeles in slugging percentage (.601) and total hits (121) this season. He's batting .276 with an on-base percentage of .380.
• Among qualified hitters in MLB, his batting average ranks 39th, his on-base percentage ranks 10th, and he is second in slugging.
• Ohtani will look for his sixth straight game with a hit in this contest. In his last five games he is hitting .421 with two doubles and four walks.
• Mookie Betts is batting .236 with 16 doubles, a triple, 11 home runs and 43 walks. He's slugging .361 with an on-base percentage of .308.
• He is 123rd in batting average, 117th in on-base percentage and 142nd in slugging in the majors.
• Will Smith has 94 hits this season and a team-best OBP of .420.
• Freddie Freeman has been key for Los Angeles with 116 hits, an OBP of .373 plus a slugging percentage of .489.

Cardinals Player Leaders

• Brendan Donovan has racked up an on-base percentage of .351 and a slugging percentage of .405. Both lead the Cardinals. He's batting .279.
• Including all the qualified hitters in MLB, his batting average is 32nd, his on-base percentage ranks 44th, and he is 101st in slugging.
• Alec Burleson is hitting .278 with 19 doubles, 14 home runs and 30 walks. He's slugging .450 with an on-base percentage of .332.
• Including all qualifying hitters, he ranks 35th in batting average, 68th in on-base percentage and 63rd in slugging percentage.
• Willson Contreras has totaled 103 hits, a team-best for the Cardinals.
• Masyn Winn has 24 doubles, eight home runs and 28 walks while hitting .267.

Dodgers vs Cardinals Head to Head

• 8/5/2025: 12-6 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 8/4/2025: 3-2 STL (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 6/8/2025: 7-3 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 6/7/2025: 2-1 STL (Favorite: Dodgers, Spread: -1.5, Total: 8, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/6/2025: 5-0 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/18/2024: 2-1 LAD (Favorite: Cardinals, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/17/2024: 5-2 STL (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/16/2024: 7-6 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 3/31/2024: 5-4 LAD (Favorite: Dodgers, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 3/30/2024: 6-5 STL (Favorite: Dodgers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)

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