Diamondbacks vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for April 4

Odds updated as of 6:11 p.m.

MLB action on Friday includes the Arizona Diamondbacks facing the Washington Nationals.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Diamondbacks vs Nationals Game Info

• Arizona Diamondbacks (4-3) vs. Washington Nationals (1-5)
• Date: Friday, April 4, 2025
• Time: 6:45 p.m. ET
• Venue: Nationals Park -- Washington, District of Columbia
• Coverage: MASN2 and ARID

Diamondbacks vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-146) | WSH: (+124)
• Spread: ARI: -1.5 (+106) | WSH: +1.5 (-128)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Diamondbacks vs Nationals Probable Starting Pitchers

Probable Pitchers: Brandon Pfaadt (Diamondbacks) - 0-1, 4.50 ERA vs Jake Irvin (Nationals) - 0-0, 3.60 ERA

The Diamondbacks will give the nod to Brandon Pfaadt (0-1) against the Nationals and Jake Irvin. Pfaadt and his team failed to cover the spread in his only opportunity this season as a starter. Pfaadt's team lost his only start as a favorite this season. Irvin has started only one game with a set spread, which the Nationals failed to cover. The Nationals were the underdog on the moneyline for one Irvin start this season -- they lost.

Diamondbacks vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Diamondbacks win (60.1%)

Diamondbacks vs Nationals Moneyline

• Washington is a +124 underdog on the moneyline, while Arizona is a -146 favorite on the road.

Diamondbacks vs Nationals Spread

• The Nationals are at +1.5 on the runline against the Diamondbacks. The Nationals are -128 to cover the spread, and the Diamondbacks are +106.

Diamondbacks vs Nationals Over/Under

• A combined run total of 8.5 has been set for Diamondbacks-Nationals on April 4, with the over at -102 and the under at -120.

Bet on Arizona Diamondbacks vs. Washington Nationals on FanDuel today!

Diamondbacks vs Nationals Betting Trends

• The Diamondbacks have been favorites in five games this season and have come away with the win three times (60%) in those contests.
• Arizona has not played a game this season with better moneyline odds than -146.
• The Diamondbacks and their opponents have gone over in four of their seven games with a total set by sportsbooks this season.
• In seven games with a line this season, the Diamondbacks have a mark of 4-3-0 against the spread.
• The Nationals are 1-4 in games they were listed as the moneyline underdog (winning 20% of those games).
• Washington has not yet won a game when entering as a moneyline underdog with odds of +124 or longer in four chances.
• The Nationals have played in six games with a set over/under, and have combined with their opponents to go over the total two times (2-4-0).
• The Nationals have a 1-5-0 record ATS this season (covering only 16.7% of the time).

Diamondbacks Player Leaders

• Eugenio Suarez leads Arizona in total hits (six) this season while batting .250 with six extra-base hits. He has an on-base percentage of .379 and a slugging percentage of .917.
• Among all qualifying hitters in MLB, he is 81st in batting average, 44th in on-base percentage, and third in slugging.
• Geraldo Perdomo leads Arizona in slugging percentage (.480) thanks to two extra-base hits. He's batting .320 with an on-base percentage of .321.
• He ranks 29th in batting average, 78th in on-base percentage and 62nd in slugging among qualifying hitters.
• Josh Naylor has an OPS of .873, fueled by an OBP of .433 and a team-best slugging percentage of .440 this season.
• Lourdes Gurriel Jr. is batting .222 with a .250 OBP and six RBI for Arizona this season.
• Gurriel has hit safely in two games in a row. In his last five games he is batting .235 with a double, two home runs, a walk and five RBI.

Nationals Player Leaders

• Keibert Ruiz has put up an on-base percentage of .435, a slugging percentage of .714, and has eight hits, all club-highs for the Nationals (while batting .381).
• He is 13th in batting average, 23rd in on-base percentage and 16th in slugging percentage among all qualified hitters in the big leagues.
• Ruiz takes a six-game hitting streak into this game. During his last six games he is batting .381 with a double, two home runs, a walk and five RBI.
• C.J. Abrams has two doubles, two home runs and a walk while batting .280. He's slugging .600 with an on-base percentage of .308.
• Including all qualified players, he is 55th in batting average, 92nd in on-base percentage and 33rd in slugging percentage.
• Nate Lowe is hitting .304 with two doubles, two home runs and two walks.
• Amed Rosario is batting .375 with a home run.

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