Diamondbacks vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for July 21

Odds updated as of 10:12 a.m.

Tuesday's slate in the MLB includes a matchup between the Arizona Diamondbacks and the Athletics.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this game.

Diamondbacks vs Athletics Game Info

• Arizona Diamondbacks (51-49) vs. Athletics (43-57)
• Date: Tuesday, July 21, 2026
• Time: 9:40 p.m. ET
• Venue: Chase Field -- Phoenix, Arizona
• Coverage: Dbacks.TV and NBCS-CA

Diamondbacks vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: ARI: (-134) | OAK: (+116)
• Spread: ARI: -1.5 (+155) | OAK: +1.5 (-188)
• Total: 9.5 -- Over: (-120) | Under: (-102)

Diamondbacks vs Athletics Probable Starting Pitchers

Probable Pitchers: Kohl Drake (Diamondbacks) - 0-0, 0.00 ERA vs Jack Perkins (Athletics) - 2-5, 6.87 ERA

This contest's pitching matchup is set, as the Diamondbacks will send Kohl Drake to the mound, while Jack Perkins (2-5) will take the ball for the Athletics. Drake did not pitch as the moneyline favorite in any games last season. The Athletics have gone 1-5-0 ATS in Perkins' six starts with a set spread. The Athletics were named the moneyline underdog for one Perkins start this season -- they lost.

Diamondbacks vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Athletics win (55.1%)

Diamondbacks vs Athletics Moneyline

• The Diamondbacks vs Athletics moneyline has the Diamondbacks as a -134 favorite, while the Athletics are a +116 underdog on the road.

Diamondbacks vs Athletics Spread

• The Diamondbacks are 1.5-run favorites on the runline against the Athletics. The Diamondbacks are +155 to cover, while the Athletics are -188 to cover.

Diamondbacks vs Athletics Over/Under

• The over/under for Diamondbacks-Athletics on July 21 is 9.5. The over is -120, and the under is -102.

Bet on Arizona Diamondbacks vs. Athletics on FanDuel today!

Diamondbacks vs Athletics Betting Trends

• The Diamondbacks have been favorites in 42 games this season and have come away with the win 25 times (59.5%) in those contests.
• This season, the Diamondbacks have come away with a win 12 times in 20 chances when named as a favorite of at least -134 or better on the moneyline.
• The Diamondbacks and their opponents have hit the over in 41 of their 99 games with a total this season.
• The Diamondbacks have posted a record of 54-45-0 against the spread this season.
• The Athletics have been the moneyline underdog 63 total times this season. They've finished 27-36 in those games.
• In games they have played as a moneyline underdog with odds of +116 or longer, the Athletics have a record of 12-18 (40%).
• The Athletics have played in 100 games with an over/under set, and have combined with their opponents to go over the total 49 times (49-50-1).
• The Athletics have a 46-54-0 record against the spread this season (covering 46% of the time).

Diamondbacks Player Leaders

• Ketel Marte leads Arizona in slugging percentage (.461) thanks to 40 extra-base hits. He has a .258 batting average and an on-base percentage of .312.
• Among all qualified hitters in baseball, he ranks 70th in batting average, 108th in on-base percentage, and 49th in slugging.
• Marte has recorded a base hit in four games in a row. In his last five games he is hitting .238 with a home run, a walk and four RBIs.
• Corbin Carroll has 89 hits, which leads Arizona batters this season. He's batting .250 with 44 extra-base hits. He's also slugging .480 with an on-base percentage of .344.
• Among qualifying hitters, his batting average ranks him 86th, his on-base percentage 57th, and his slugging percentage 31st.
• Geraldo Perdomo has 81 hits this season and a team-best OBP of .356.
• Perdomo enters this game with two games in a row with at least one hit. In his last five games he is batting .188 with a home run, five walks and two RBIs.
• Ildemaro Vargas is batting .258 with a .301 OBP and 47 RBI for Arizona this season.
• Vargas has safely hit in three games in a row. In his last five games he is batting .278 with a double, a triple and an RBI.

Athletics Player Leaders

• Tyler Soderstrom is batting .247 with 21 doubles, two triples, 16 home runs and 45 walks. He's slugging .478 with an on-base percentage of .345.
• Including all the qualified hitters in the majors, his batting average puts him 87th, his on-base percentage ranks 55th, and he is 32nd in slugging.
• Soderstrom takes a four-game hitting streak into this game. In his last five games he is hitting .300 with two home runs, a walk and five RBIs.
• Shea Langeliers' .490 slugging percentage paces his team. He has a batting average of .260 with an on-base percentage of .329.
• Including all qualifying hitters, his batting average puts him 64th, his on-base percentage ranks 79th, and he is 26th in slugging.
• Jacob Wilson is batting .292 with 10 doubles, a triple, six home runs and 11 walks.
• Carlos Cortes is hitting .282 with 12 doubles, a triple, seven home runs and 22 walks.

Diamondbacks vs Athletics Head to Head

• 7/20/2026: 5-2 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/3/2025: 6-4 ARI (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 8/2/2025: 7-2 ARI (Favorite: Athletics, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 8/1/2025: 5-1 OAK (Favorite: Athletics, Spread: -1.5, Total: 10, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 6/30/2024: 5-1 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/29/2024: 3-0 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 8.5, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/28/2024: 9-4 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/17/2023: 5-3 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 5/16/2023: 9-8 OAK (Favorite: Diamondbacks, Spread: -1.5, Total: 9.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 5/15/2023: 5-2 ARI (Favorite: Diamondbacks, Spread: -1.5, Total: 9, Favorite Moneyline: -220, Underdog Moneyline: +184)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!