Cubs vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for July 18

Odds updated as of 2:11 a.m.

Friday's slate in the MLB includes a matchup between the Chicago Cubs and the Boston Red Sox.

All the info you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cubs vs Red Sox Game Info

• Chicago Cubs (57-39) vs. Boston Red Sox (53-45)
• Date: Friday, July 18, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MLB Network, MARQ, and NESN

Cubs vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-134) | BOS: (+114)
• Spread: CHC: -1.5 (+146) | BOS: +1.5 (-178)
• Total: 8.5 -- Over: (-100) | Under: (-122)

Cubs vs Red Sox Probable Starting Pitchers

Probable Pitchers: Colin Rea (Cubs) - 7-3, 3.91 ERA vs Lucas Giolito (Red Sox) - 6-1, 3.36 ERA

The probable starters are Colin Rea (7-3) for the Cubs and Lucas Giolito (6-1) for the Red Sox. Rea and his team are 9-5-0 ATS this season when he starts. Rea's team is 5-3 this season when he starts and they are the moneyline favorite. When Giolito starts, the Red Sox have gone 9-4-0 against the spread. The Red Sox have been the underdog on the moneyline in six of Giolito's starts this season, and they went 4-2 in those games.

Cubs vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (54.4%)

Cubs vs Red Sox Moneyline

• Boston is the underdog, +114 on the moneyline, while Chicago is a -134 favorite at home.

Cubs vs Red Sox Spread

• The Red Sox are +1.5 on the run line against the Cubs. The Red Sox are -178 to cover, and the Cubs are +146.

Cubs vs Red Sox Over/Under

• The over/under for Cubs-Red Sox on July 18 is 8.5. The over is -100, and the under is -122.

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Cubs vs Red Sox Betting Trends

• The Cubs have been favorites in 60 games this season and have come away with the win 42 times (70%) in those contests.
• This season Chicago has come away with a win 31 times in 43 chances when named as a favorite of at least -134 on the moneyline.
• The Cubs and their opponents have hit the over in 48 of their 93 games with a total set by oddsmakers this season.
• The Cubs have posted a record of 46-47-0 against the spread this season.
• The Red Sox have won 46.7% of the games this season they were the underdog on the moneyline (14-16).
• Boston is 7-8 (winning 46.7% of its games) when it has played as a moneyline underdog of +114 or longer.
• The Red Sox have had an over/under set by bookmakers 97 times, and have combined with opponents to go over the total in 47 of those games (47-47-3).
• The Red Sox have covered 54.6% of their games this season, going 53-44-0 against the spread.

Cubs Player Leaders

• Kyle Tucker leads Chicago with an OBP of .384, plus a team-best slugging percentage of .499. He's batting .280 on the season.
• Among qualifying hitters in MLB, his batting average ranks 39th, his on-base percentage ranks seventh, and he is 21st in slugging.
• Pete Crow-Armstrong is hitting .265 with 21 doubles, four triples, 25 home runs and 18 walks, while slugging .544 with an on-base percentage of .302.
• Among qualifying batters, he ranks 64th in batting average, 124th in on-base percentage and 10th in slugging percentage.
• Seiya Suzuki is batting .263 with a .547 slugging percentage and 77 RBI this year.
• Suzuki has logged a hit or more in two straight games. During his last five outings he is hitting .300 with two doubles and a walk.
• Nico Hoerner is batting .283 with a .331 OBP and 39 RBI for Chicago this season.

Red Sox Player Leaders

• Ceddanne Rafaela has totaled 86 hits, a team-best for the Red Sox. He's batting .271 and slugging .483 with an on-base percentage of .314.
• Including all the qualified hitters in the big leagues, he is 58th in batting average, 109th in on-base percentage and 32nd in slugging percentage.
• Rafaela heads into this game on a 10-game hitting streak. In his last 10 games he is hitting .421 with six doubles, five home runs, a walk and 15 RBIs.
• Jarren Duran's .318 OBP and .431 slugging percentage both lead his team. He has a batting average of .258.
• Including all qualified players, he ranks 83rd in batting average, 101st in on-base percentage and 75th in slugging percentage.
• Wilyer Abreu is hitting .256 with 11 doubles, 18 home runs and 29 walks.
• Trevor Story is hitting .257 with 13 doubles, 15 home runs and 18 walks.

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