Cubs vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 13

Odds updated as of 11:12 p.m.

The MLB schedule on Sunday includes the Chicago Cubs taking on the Pittsburgh Pirates.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Pirates Game Info

• Chicago Cubs (83-66) vs. Pittsburgh Pirates (74-75)
• Date: Sunday, September 13, 2026
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and SportsNet PT

Cubs vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-144) | PIT: (+122)
• Spread: CHC: -1.5 (+168) | PIT: +1.5 (-205)
• Total: 6.5 -- Over: (-110) | Under: (-110)

Cubs vs Pirates Probable Starting Pitchers

Probable Pitchers: Matthew Boyd (Cubs) - 8-4, 4.03 ERA vs Bubba Chandler (Pirates) - 7-9, 4.25 ERA

This contest's pitching matchup is set, as the Cubs will send Matthew Boyd (8-4) to the mound, while Bubba Chandler (7-9) will answer the bell for the Pirates. When Boyd starts, his team is 9-9-0 against the spread this season. When Boyd starts a game and his team is the favorite on the moneyline, they have a record of 8-4. The Pirates are 15-12-0 against the spread when Chandler starts. The Pirates have a 7-10 record in Chandler's 17 starts this season when they were the moneyline underdog.

Cubs vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (56.2%)

Cubs vs Pirates Moneyline

• Chicago is the favorite, -144 on the moneyline, while Pittsburgh is a +122 underdog on the road.

Cubs vs Pirates Spread

• The Cubs are hosting the Pirates and are favored by 1.5 runs on the spread. The Cubs are +168 to cover the runline, with the Pirates being -205.

Cubs vs Pirates Over/Under

• A total of 6.5 runs has been set for the Cubs-Pirates contest on Sept. 13, with the over available at -110 and the under at -110.

Bet on Chicago Cubs vs. Pittsburgh Pirates on FanDuel today!

Cubs vs Pirates Betting Trends

• The Cubs have been chosen as favorites in 96 games this year and have walked away with the win 55 times (57.3%) in those games.
• Chicago has a record of 30-19 when favored by -144 or more this year.
• The Cubs and their opponents have gone over the total this season in 80 of their 144 opportunities.
• The Cubs are 69-75-0 against the spread in their 144 games with a line set by sportsbooks this season.
• The Pirates have been the moneyline underdog 69 total times this season. They've finished 30-39 in those games.
• When it has played as a moneyline underdog with odds of +122 or longer, Pittsburgh has a record of 8-15 (34.8%).
• The Pirates have combined with opponents to go over the total 76 times this season for a 76-67-4 record against the over/under.
• The Pirates have covered 48.3% of their games this season, going 71-76-0 against the spread.

Cubs Player Leaders

• Pete Crow-Armstrong has 160 hits and an OBP of .373 to go with a slugging percentage of .566. All three of those stats are tops among Chicago hitters this season. He has a .279 batting average, as well.
• He ranks 25th in batting average, 10th in on-base percentage, and second in slugging among qualifying hitters in baseball.
• Alex Bregman has 30 doubles, a triple, 25 home runs and 71 walks. He's batting .264 and slugging .450 with an on-base percentage of .353.
• He ranks 56th in batting average, 40th in on-base percentage and 47th in slugging among qualifying hitters.
• Bregman brings a three-game streak with at least one hit into this contest. During his last five outings he is batting .412 with two doubles, a home run, two walks and three RBIs.
• Seiya Suzuki has collected 134 base hits, an OBP of .370 and a slugging percentage of .480 this season.
• Nico Hoerner is batting .267 with a .320 OBP and 67 RBI for Chicago this season.
• Hoerner has hit safely in four games in a row. During his last five outings he is batting .286 with a double and three RBIs.

Pirates Player Leaders

• Bryan Reynolds has put up an on-base percentage of .368, a team-best for the Pirates. He's batting .264 and slugging .429.
• Including all the qualified players in the majors, he ranks 56th in batting average, 17th in on-base percentage and 65th in slugging percentage.
• Brandon Lowe's 139 hits lead his team. He has a batting average of .257 while slugging .474 with an on-base percentage of .327.
• Including all qualifying hitters, he ranks 67th in batting average, 70th in on-base percentage and 28th in slugging percentage.
• Nick Gonzales has a team-high OBP (.368) and slugging percentage (.392).
• Ryan O'Hearn is hitting .268 with 15 doubles, 18 home runs and 31 walks.

Cubs vs Pirates Head to Head

• 9/12/2026: 4-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 9.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 9/11/2026: 12-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -190, Underdog Moneyline: +160)
• 7/26/2026: 8-7 PIT (Favorite: Pirates, Spread: -1.5, Total: 9, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 7/25/2026: 11-0 CHC (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 7/24/2026: 3-2 CHC (Favorite: Pirates, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/28/2026: 7-2 CHC (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/27/2026: 10-4 CHC (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 5/26/2026: 12-1 PIT (Favorite: Pirates, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/25/2026: 2-1 PIT (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 4/12/2026: 7-6 CHC (Favorite: Cubs, Spread: -1.5, Total: 12.5, Favorite Moneyline: -134, Underdog Moneyline: +116)

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