Cubs vs Pirates Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 16

Odds updated as of 8:11 a.m.

The Saturday schedule in MLB includes a matchup between the Chicago Cubs and the Pittsburgh Pirates.

We've got you covered, in terms of the vital information about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cubs vs Pirates Game Info

• Chicago Cubs (68-53) vs. Pittsburgh Pirates (52-71)
• Date: Saturday, August 16, 2025
• Time: 2:20 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: Fox Sports 1, MARQ, and SportsNet PT

Cubs vs Pirates Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-220) | PIT: (+184)
• Spread: CHC: -1.5 (-111) | PIT: +1.5 (-108)
• Total: 9 -- Over: (-115) | Under: (-105)

Cubs vs Pirates Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 8-5, 3.19 ERA vs Mike Burrows (Pirates) - 1-4, 4.66 ERA

The Cubs will give the nod to Shota Imanaga (8-5, 3.19 ERA), who is eyeing win No. 9 on the season, and the Pirates will turn to Mike Burrows (1-4, 4.66 ERA). Imanaga's team is 8-8-0 against the spread in his starts this season. Imanaga's team is 6-4 this season when he starts and they are the moneyline favorite. The Pirates have gone 7-6-0 against the spread when Burrows starts. The Pirates have a 4-7 record in Burrows' 11 starts this season when they were the underdog on the moneyline.

Cubs vs Pirates Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (65%)

Cubs vs Pirates Moneyline

• The Cubs vs Pirates moneyline has Chicago as a -220 favorite, while Pittsburgh is a +184 underdog on the road.

Cubs vs Pirates Spread

• The Cubs are 1.5-run home favorites on the runline against the Pirates. The Cubs are -111 to cover, and the Pirates are -108.

Cubs vs Pirates Over/Under

• The over/under for Cubs-Pirates on Aug. 16 is 9. The over is -115, and the under is -105.

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Cubs vs Pirates Betting Trends

• The Cubs have been victorious in 51, or 64.6%, of the 79 contests they have been chosen as favorites in this season.
• This season Chicago has been victorious 10 times in 11 chances when named as a favorite of at least -220 on the moneyline.
• The Cubs and their opponents have hit the over in 56 of their 117 games with a total set by oddsmakers this season.
• The Cubs have posted a record of 55-62-0 against the spread this season.
• The Pirates have won 33 of the 79 games they were listed as the moneyline underdog this season (41.8%).
• Pittsburgh is 4-6 (winning 40% of its games) when it has played as a moneyline underdog of +184 or longer.
• The Pirates have combined with opponents to hit the over on the total 46 times this season for a 46-65-4 record against the over/under.
• The Pirates have covered 52.2% of their games this season, going 60-55-0 against the spread.

Cubs Player Leaders

• Kyle Tucker leads Chicago with an OBP of .376 this season while batting .263 with 78 walks and 77 runs scored. He has a slugging percentage of .454.
• Among all qualified hitters in the majors, he is 65th in batting average, 11th in on-base percentage, and 59th in slugging.
• Pete Crow-Armstrong leads Chicago with 119 hits. He is batting .259 this season and has 63 extra-base hits. He's also slugging .523 with an on-base percentage of .297.
• He is 77th in batting average, 141st in on-base percentage and 12th in slugging among qualified hitters.
• Seiya Suzuki is batting .249 with a .502 slugging percentage and 85 RBI this year.
• Nico Hoerner has an OPS of .714, fueled by an OBP of .339 and a team-best slugging percentage of .375 this season.
• Hoerner brings a three-game hitting streak into this game. In his last five games he is hitting .350 with .

Pirates Player Leaders

• Bryan Reynolds has racked up a team-best slugging percentage (.401) while leading the Pirates in hits (111). He's batting .244 and with an on-base percentage of .302.
• Including all qualifying hitters, he is 113th in batting average, while his on-base percentage is 129th and he is 105th in slugging.
• Andrew McCutchen paces his team with a .330 OBP. He has a batting average of .243 while slugging .377.
• Including all qualifying players, he ranks 117th in batting average, 72nd in on-base percentage and 135th in slugging percentage.
• Isiah Kiner-Falefa is hitting .269 with 17 doubles, two triples, a home run and 16 walks.
• Tommy Pham has 12 doubles, a triple, five home runs and 32 walks while hitting .263.

Cubs vs Pirates Head to Head

• 8/15/2025: 3-2 PIT (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 6/15/2025: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 6/14/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7, Favorite Moneyline: -235, Underdog Moneyline: +194)
• 6/13/2025: 2-1 PIT (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 6/12/2025: 3-2 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 5/1/2025: 8-3 CHC (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/30/2025: 4-3 PIT (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 4/29/2025: 9-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 9/4/2024: 12-0 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -210, Underdog Moneyline: +176)
• 9/3/2024: 5-0 PIT (Favorite: Pirates, Spread: -1.5, Total: 7.5, Favorite Moneyline: -122, Underdog Moneyline: +104)

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