Cubs vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for June 29

Odds updated as of 4:12 a.m.

The Monday schedule in MLB includes a matchup between the Chicago Cubs and the San Diego Padres.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important info about this matchup.

Cubs vs Padres Game Info

• Chicago Cubs (46-38) vs. San Diego Padres (43-39)
• Date: Monday, June 29, 2026
• Time: 8:05 p.m. ET
• Venue: Wrigley Field -- Chicago, Illinois
• Coverage: MARQ and Padres.TV

Cubs vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CHC: (-154) | SD: (+130)
• Spread: CHC: -1.5 (+122) | SD: +1.5 (-146)
• Total: 11.5 -- Over: (-114) | Under: (-106)

Cubs vs Padres Probable Starting Pitchers

Probable Pitchers: Shota Imanaga (Cubs) - 5-6, 4.40 ERA vs TBA (Padres)

Shota Imanaga (5-6) will take the mound for the Cubs in this matchup. The Padres, however, have yet to list a starting pitcher. Imanaga and his team have a record of 5-11-0 against the spread when he starts. When Imanaga starts a game and his team is the favorite on the moneyline, they have a record of 6-8.

Cubs vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cubs win (61.7%)

Cubs vs Padres Moneyline

• Chicago is a -154 favorite on the moneyline, while San Diego is a +130 underdog on the road.

Cubs vs Padres Spread

• The Cubs are hosting the Padres and are favored by 1.5 runs on the spread. The Cubs are +122 to cover the runline, with the Padres being -146.

Cubs vs Padres Over/Under

• The over/under for Cubs-Padres on June 29 is 11.5. The over is -114, and the under is -106.

Bet on Chicago Cubs vs. San Diego Padres on FanDuel today!

Cubs vs Padres Betting Trends

• The Cubs have been victorious in 30, or 55.6%, of the 54 contests they have been chosen as favorites in this season.
• This year Chicago has won 13 of 20 games when listed as at least -154 on the moneyline.
• The Cubs and their opponents have gone over the total this season in 44 of their 82 opportunities.
• The Cubs are 34-48-0 against the spread in their 82 games with a line set by sportsbooks this season.
• The Padres have been the moneyline underdog 45 total times this season. They've gone 22-23 in those games.
• When playing as a moneyline underdog with odds of +130 or longer, San Diego has a 2-8 record (winning only 20% of its games).
• The Padres have played in 82 games with a set over/under, and have combined with their opponents to go over the total 36 times (36-45-1).
• The Padres have a 45-37-0 record against the spread this season (covering 54.9% of the time).

Cubs Player Leaders

• Pete Crow-Armstrong leads Chicago in slugging percentage (.505) and total hits (88) this season. He's batting .278 with an on-base percentage of .364.
• He is 36th in batting average, 30th in on-base percentage, and 23rd in slugging among all qualifying hitters in baseball.
• Nico Hoerner has 21 doubles, four home runs and 34 walks. He's batting .242 and slugging .342 with an on-base percentage of .317.
• He is 100th in batting average, 103rd in on-base percentage and 137th in slugging among qualified hitters.
• Hoerner enters this matchup looking to extend his two-game hit streak. During his last five outings he is batting .350 with three doubles, a walk and an RBI.
• Ian Happ is batting .224 with a .458 slugging percentage and 41 RBI this year.
• Michael Busch leads Chicago with an OBP of .370 this season while batting .236 with 58 walks and 33 runs scored.

Padres Player Leaders

• Manny Machado is hitting .188 with 15 doubles, 15 home runs and 36 walks. He's slugging .392 with an on-base percentage of .272.
• Including all qualified hitters, he ranks 155th in batting average, while his on-base percentage ranks 149th and he is 105th in slugging.
• Fernando Tatis Jr. paces his team with a .347 on-base percentage, and has a club-leading .366 slugging percentage. He has a batting average of .283.
• Including all qualified hitters, his batting average places him 27th, his on-base percentage ranks 52nd, and he is 126th in slugging.
• Gavin Sheets has collected 55 hits, a team-best for the Padres.
• Xander Bogaerts is hitting .229 with four doubles, eight home runs and 34 walks.

Cubs vs Padres Head to Head

• 4/29/2026: 5-4 CHC (Favorite: Padres, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/28/2026: 8-3 CHC (Favorite: Cubs, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: +100)
• 4/27/2026: 9-7 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/2/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 10/1/2025: 3-0 SD (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/30/2025: 3-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 6.5, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 4/16/2025: 4-2 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 4/15/2025: 2-1 CHC (Favorite: Cubs, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/14/2025: 10-4 SD (Favorite: Padres, Spread: -1.5, Total: 7.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 4/6/2025: 8-7 SD (Favorite: Cubs, Spread: -1.5, Total: 7.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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