Creighton vs DePaul Basketball Prediction, Odds, Picks, Best Bets for Big East Tournament

The No. 10 seed DePaul Blue Demons (14-18, 4-16 Big East) will play in the Big East tournament against the No. 2 seed Creighton Bluejays (22-9, 15-5 Big East) on Thursday at Madison Square Garden, tipping off at 7 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Creighton vs. DePaul Game Info and Odds

• Game day: Thursday, March 13, 2025
• Game time: 7 p.m. ET
• TV channel: Fox Sports 1
• Location: New York City, New York
• Arena: Madison Square Garden

Before you wager on Thursday's Creighton-DePaul spread (Creighton -12.5) or over/under (142.5 points), check out the betting insights and trends below.

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Creighton vs. DePaul: ATS Betting Stats and Trends

• Creighton has put together a 20-11-0 ATS record so far this year.
• DePaul has put together a 15-17-0 ATS record so far this season.
• When the spread is set as 12.5 or more this season, Creighton (2-4) covers a lower percentage of those games when it is the favorite (33.3%) than DePaul (4-3) does as the underdog (57.1%).
• Against the spread, the Bluejays have played worse at home, covering 11 times in 17 home games, and nine times in 11 road games.
• The Blue Demons' winning percentage against the spread at home is .474 (9-10-0). Away, it is .417 (5-7-0).
• Creighton has 16 wins against the spread in 20 conference games this season.
• DePaul has beaten the spread nine times in 21 Big East games.

Creighton vs. DePaul: Moneyline Betting Stats

• Creighton has won in 16, or 80%, of the 20 contests it has been named as the moneyline favorite in this year.
• The Bluejays have not lost in four games this year when favored by -901 or better on the moneyline.
• DePaul has won 19% of the games this season it was the moneyline underdog (4-17).
• The Blue Demons have played in five games as a moneyline underdog with odds of +590 or longer without claiming a victory.
• Creighton has an implied victory probability of 90% according to the moneyline set by oddsmakers for this matchup.

Creighton vs. DePaul Head-to-Head Comparison

• Creighton averages 75.4 points per game (134th in college basketball) while giving up 69 per contest (90th in college basketball). It has a +197 scoring differential overall and outscores opponents by 6.4 points per game.
• Ryan Kalkbrenner is 29th in the country with a team-leading 19.4 points per game.
• DePaul has been outscored by 1.4 points per game (posting 72.5 points per game, 217th in college basketball, while allowing 73.9 per outing, 242nd in college basketball) and has a -43 scoring differential.
• CJ Gunn leads DePaul, scoring 12.7 points per game (575th in college basketball).
• The 34.9 rebounds per game the Bluejays average rank 40th in the nation, and are four more than the 30.9 their opponents collect per outing.
• Kalkbrenner is 35th in college basketball action with nine rebounds per game to lead the Bluejays.
• The Blue Demons record 31.3 rebounds per game (215th in college basketball), compared to the 31.9 of their opponents.
• N.J. Benson's six rebounds per game lead the Blue Demons and rank 322nd in the country.
• Creighton scores 99 points per 100 possessions (96th in college basketball), while allowing 90.7 points per 100 possessions (106th in college basketball).
• The Blue Demons average 94.7 points per 100 possessions on offense (203rd in college basketball), and concede 96.5 points per 100 possessions (268th in college basketball).

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