Cavaliers vs. Lakers Prediction, Odds, Picks, Best Bets for Jan. 28

Cavaliers vs. Lakers Game Info

• Date: Wednesday, January 28, 2026
• Time: 7 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: ESPN and SportsNet LA

Two of the NBA's top scorers square off when Donovan Mitchell (fifth, 29.5 PPG) and the Cleveland Cavaliers (28-20) host Luka Doncic (first, 33.8 PPG) and the Los Angeles Lakers (28-17) on Wednesday, January 28, 2026 at 7 p.m. ET on ESPN and SportsNet LA. The Cavaliers are 3-point favorites. The matchup has a point total of 236.5.

Cavaliers vs. Lakers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Lakers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (68.3%)

Cavaliers vs. Lakers Betting Trends

• The Cavaliers have covered the spread 19 times in 48 games with a set spread.
• The Lakers are 24-20-1 against the spread this season.
• Cavaliers games have gone over the total 22 times out of 45 chances this season.
• Lakers games this year have gone over the total in 26 of 45 opportunities (57.8%).
• Cleveland has done a better job covering the spread in road games (10-11-0) than it has at home (9-18-0).
• The Cavaliers have hit the over on the total in 11 of 27 home games (40.7%). They've fared better in away games, eclipsing the total in 11 of 21 matchups (52.4%).
• Against the spread, Los Angeles has had better results on the road (14-11-0) than at home (10-9-1).
• Lakers games have gone above the over/under 75% of the time at home (15 of 20), and 44% of the time on the road (11 of 25).

Cavaliers Leaders

• Mitchell's numbers on the season are 29.5 points, 4.8 boards and 5.8 assists per contest, shooting 48.5% from the field and 38.5% from downtown, with an average of 3.8 made 3-pointers (second in NBA).
• Jaylon Tyson's numbers on the season are 13.7 points, 5.6 boards and 2.3 assists per game, shooting 51.3% from the floor and 46.6% from downtown (third in league), with an average of 2 made 3-pointers.
• Jarrett Allen averages 13.3 points, 7.8 rebounds and 1.9 assists.
• De'Andre Hunter's numbers on the season are 13.8 points, 4.3 boards and 2.1 assists per game, shooting 42% from the field and 30.6% from downtown, with an average of 1.7 made treys.
• Craig Porter Jr. is averaging 4.8 points, 3 assists and 3.6 boards.

Lakers Leaders

• Doncic is averaging 33.8 points, 7.8 boards and 8.8 assists for the Lakers.
• Per game, LeBron James gets the Lakers 22.4 points, 6 rebounds and 6.7 assists. He also averages 1.1 steals and 0.6 blocks.
• The Lakers receive 13.4 points per game from Deandre Ayton, plus 8.6 boards and 0.8 assists.
• The Lakers get 9.5 points per game from Jake LaRavia, plus 4.3 rebounds and 2 assists.
• Per game, Marcus Smart gives the Lakers 10.1 points, 3.1 rebounds and 2.8 assists, plus 1.3 steals and 0.4 blocks.

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