Cavaliers vs. Grizzlies Prediction, Odds, Picks, Best Bets for Nov. 15

Cavaliers vs. Grizzlies Game Info

• Date: Saturday, November 15, 2025
• Time: 5 p.m. ET
• Venue: Rocket Arena -- Cleveland, Ohio
• Coverage: FDSOH, FDSSE, and NBA TV

The Memphis Grizzlies (4-9) visit the Cleveland Cavaliers (8-5) after losing three road games in a row. The Cavaliers are double-digit favorites by 10 points in the contest, which tips at 5 p.m. ET on Saturday, November 15, 2025. The matchup's point total is 237.5.

Cavaliers vs. Grizzlies Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Cavaliers vs. Grizzlies Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Cavaliers win (74.7%)

Cavaliers vs. Grizzlies Betting Trends

• The Cavaliers are 5-8-0 against the spread this season.
• The Grizzlies have three wins against the spread in 13 games this year.
• Cavaliers games have gone over the total eight times this season.
• Grizzlies games this season have eclipsed the over/under five times in 13 opportunities (38.5%).
• Against the spread, Cleveland has performed worse at home, covering two times in six home games, and three times in seven road games.
• In home games, the Cavaliers eclipse the total 50% of the time (three of six games). They hit the over more consistently in road games, going over the total in 71.4% of games (five of seven).
• This season, Memphis is 3-5-0 at home against the spread (.375 winning percentage). Away, it is 0-5-0 ATS (.000).
• In terms of the over/under, Grizzlies games have finished over three of eight times at home (37.5%), and two of five away (40%).

Cavaliers Leaders

• Donovan Mitchell is averaging 30.5 points, 4.5 boards and 5.5 assists. Defensively, he averages 1.5 steals and 0.5 blocked shots.
• Evan Mobley averages 19 points, 8.7 boards and 4.2 assists, shooting 47.1% from the field and 34.5% from beyond the arc, with 1.7 made 3-pointers per contest.
• Jarrett Allen is averaging 15.5 points, 7.9 boards and 1.7 assists. Defensively, he averages 1.3 steals and 0.9 blocked shots.
• De'Andre Hunter is averaging 18.9 points, 3.1 assists and 4.9 rebounds.
• Jaylon Tyson is averaging 11.1 points, 4 rebounds and 1.8 assists. At the other end, he averages 1.3 steals and 0.8 blocked shots.

Grizzlies Leaders

• Per game, Ja Morant gives the Grizzlies 18.9 points, 3.7 rebounds and 8.1 assists. He also averages 1.1 steals and 0.1 blocks.
• Cedric Coward's numbers on the season are 14.3 points, 5.9 rebounds and 3.1 assists per game. He is draining 48.4% of his shots from the floor and 37.5% from 3-point range, with an average of 1.6 treys.
• The Grizzlies are receiving 17.2 points, 5.2 rebounds and 1.3 assists per game from Jaren Jackson Jr.
• Santi Aldama averages 12.7 points, 6.5 boards and 2.5 assists. He is draining 45.7% of his shots from the floor and 30% from 3-point range, with 1.4 treys per game.
• Jock Landale's numbers on the season are 10.7 points, 5.5 boards and 1.8 assists per game. He is sinking 56.8% of his shots from the floor and 48.5% from beyond the arc, with an average of 1.2 triples.

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