Cardinals vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 1

Odds updated as of 12:12 a.m.

The MLB slate on Monday includes the St. Louis Cardinals taking on the Athletics.

We've got you covered, in terms of the vital information about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Cardinals vs Athletics Game Info

• St. Louis Cardinals (68-70) vs. Athletics (63-75)
• Date: Monday, September 1, 2025
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: FDSMW and NBCS-CA

Cardinals vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-148) | OAK: (+126)
• Spread: STL: -1.5 (+140) | OAK: +1.5 (-170)
• Total: 8 -- Over: (-106) | Under: (-114)

Cardinals vs Athletics Probable Starting Pitchers

Probable Pitchers: Sonny Gray (Cardinals) - 12-7, 4.19 ERA vs Luis Morales (Athletics) - 2-0, 1.19 ERA

The probable pitchers are Sonny Gray (12-7) for the Cardinals and Luis Morales (2-0) for the Athletics. Gray's team is 13-12-0 against the spread in his starts this season. Gray's team has been victorious in 70.6% of the games he's started as the moneyline favorite with a record of 12-5. The Athletics are 3-1-0 against the spread when Morales starts. The Athletics have been the moneyline underdog in three of Morales' starts this season, and they went 2-1 in those matchups.

Cardinals vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (58.2%)

Cardinals vs Athletics Moneyline

• The Cardinals vs Athletics moneyline has the Cardinals as a -148 favorite, while the Athletics are a +126 underdog on the road.

Cardinals vs Athletics Spread

• The Cardinals are 1.5-run favorites on the runline against the Athletics. The Cardinals are +140 to cover, while the Athletics are -170 to cover.

Cardinals vs Athletics Over/Under

• Cardinals versus Athletics on Sept. 1 has an over/under of 8 runs, with the odds on the over -106 and the under set at -114.

Bet on St. Louis Cardinals vs. Athletics on FanDuel today!

Cardinals vs Athletics Betting Trends

• The Cardinals have been chosen as favorites in 59 games this year and have walked away with the win 30 times (50.8%) in those games.
• This season, the Cardinals have come away with a win 10 times in 17 chances when named as a favorite of at least -148 or shorter on the moneyline.
• The Cardinals and their opponents have hit the over in 69 of their 132 games with a total this season.
• The Cardinals have an against the spread mark of 67-65-0 in 132 games with a line this season.
• The Athletics have gone 45-58 in games they were listed as the moneyline underdog (winning 43.7% of those games).
• In games they have played as a moneyline underdog with odds of +126 or longer, the Athletics have a record of 18-32 (36%).
• The Athletics have played in 137 games with an over/under set, and have combined with their opponents to go over the total 69 times (69-62-6).
• The Athletics have a 72-65-0 record against the spread this season.

Cardinals Player Leaders

• Willson Contreras is hitting .253 with 30 doubles, 20 home runs and 41 walks. He has an on-base percentage of .337 and a slugging percentage of .447.
• He is 89th in batting average, 62nd in on-base percentage, and 68th in slugging among all qualified hitters in MLB.
• Contreras will look for his third straight game with a hit in this matchup. In his last five games he is hitting .105 with a home run, a walk and an RBI.
• Masyn Winn is hitting .255 with 27 doubles, nine home runs and 32 walks, while slugging .370 with an on-base percentage of .311.
• His batting average is 86th among qualified players, his on-base percentage 114th, and his slugging percentage 137th.
• Lars Nootbaar has collected 102 base hits, an OBP of .330 and a slugging percentage of .387 this season.
• Nootbaar has logged a hit or more in two straight games. During his last five outings he is hitting .350 with two doubles, a triple and two walks.
• Ivan Herrera has 11 home runs, 50 RBI and a batting average of .286 this season.
• Herrera has safely hit in six straight games. In his last 10 games he is batting .257 with a double, a home run, four walks and four RBIs.

Athletics Player Leaders

• Brent Rooker has a .496 slugging percentage, which leads the Athletics. He's batting .271 with an on-base percentage of .343.
• Including all the qualifying hitters in the majors, he is 41st in batting average, 51st in on-base percentage and 23rd in slugging percentage.
• Tyler Soderstrom is hitting .270 with 27 doubles, a triple, 23 home runs and 51 walks. He's slugging .469 with an on-base percentage of .343.
• He is currently 44th in batting average, 51st in on-base percentage and 42nd in slugging percentage among all qualifying hitters.
• Shea Langeliers is leading the Athletics with 105 hits.
• Nick Kurtz is hitting .308 with 23 doubles, two triples, 27 home runs and 53 walks.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!