Brewers vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 4

Odds updated as of 9:12 a.m.

The MLB's Friday schedule includes the Milwaukee Brewers taking on the Cincinnati Reds.

We've got you covered, in terms of the vital info about this matchup before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Brewers vs Reds Game Info

• Milwaukee Brewers (87-54) vs. Cincinnati Reds (67-73)
• Date: Friday, September 4, 2026
• Time: 6:10 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Brewers.TV

Brewers vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-162) | CIN: (+136)
• Spread: MIL: -1.5 (+100) | CIN: +1.5 (-120)
• Total: 9.5 -- Over: (-110) | Under: (-110)

Brewers vs Reds Probable Starting Pitchers

Probable Pitchers: Shane Drohan (Brewers) - 7-5, 3.75 ERA vs Rhett Lowder (Reds) - 6-8, 5.14 ERA

The Brewers will give the nod to Shane Drohan (7-5) versus the Reds and Rhett Lowder (6-8). When Drohan starts, his team is 7-9-0 against the spread this season. When Drohan starts a game and his team is the favorite on the moneyline, they have a record of 8-6. The Reds have an 11-10-0 ATS record in Lowder's 21 starts that had a set spread. The Reds have been the moneyline underdog in 18 of Lowder's starts this season, and they went 10-8 in those games.

Brewers vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (68.6%)

Brewers vs Reds Moneyline

• Milwaukee is a -162 favorite on the moneyline, while Cincinnati is a +136 underdog at home.

Brewers vs Reds Spread

• The Brewers are 1.5-run road favorites on the runline against the Reds. The Brewers are +100 to cover, and the Reds are -120.

Brewers vs Reds Over/Under

• A total of 9.5 runs has been set for the Brewers-Reds contest on Sept. 4, with the over available at -110 and the under at -110.

Bet on Milwaukee Brewers vs. Cincinnati Reds on FanDuel today!

Brewers vs Reds Betting Trends

• The Brewers have been favorites in 108 games this season and have come away with the win 69 times (63.9%) in those contests.
• Milwaukee has a record of 23-12 when favored by -162 or more this year.
• The Brewers' games have gone over the total in 61 of their 141 opportunities.
• The Brewers are 74-67-0 against the spread in their 141 games with a line set by sportsbooks this season.
• The Reds have put together a 45-48 record in games they were the underdog on the moneyline (winning 48.4% of those games).
• Cincinnati has gone 9-8 when it has played as a moneyline underdog with odds of +136 or longer (52.9%).
• The Reds have played in 137 games with a set over/under, and have combined with their opponents to go over the total 73 times (73-62-2).
• The Reds have gone 71-66-0 ATS this season.

Brewers Player Leaders

• Brice Turang is batting .252 with 29 doubles, three triples, 17 home runs and 74 walks. He has an on-base percentage of .346 and a slugging percentage of .421.
• Among the qualifying hitters in MLB, his batting average ranks 75th, his on-base percentage ranks 44th, and he is 68th in slugging.
• Jake Bauers has 113 hits and an OBP of .389, both of which lead the Brewers this season. He's batting .268 and slugging .487.
• His batting average is 47th among qualified players, his on-base percentage fourth, and his slugging percentage 19th.
• William Contreras has an OPS of .743, fueled by an OBP of .341 and a team-best slugging percentage of .402 this season.
• Jackson Chourio has been key for Milwaukee with 125 hits, an OBP of .344 plus a slugging percentage of .483.

Reds Player Leaders

• Sal Stewart has a team-high slugging percentage (.485) and paces the Reds in hits (143). He's batting .266 and with an on-base percentage of .336.
• Including all the qualified hitters in the majors, his batting average ranks 52nd, his on-base percentage ranks 62nd, and he is 22nd in slugging.
• Elly De La Cruz paces his team with a .353 OBP. He has a batting average of .273 while slugging .476.
• He is currently 37th in batting average, 38th in on-base percentage and 29th in slugging percentage among all qualifying batters.
• JJ Bleday is batting .222 with 15 doubles, two triples, 22 home runs and 64 walks.
• Tyler Stephenson is batting .249 with 19 doubles, 14 home runs and 42 walks.

Brewers vs Reds Head to Head

• 7/2/2026: 7-2 CIN (Favorite: Brewers, Spread: -1.5, Total: 7, Favorite Moneyline: -205, Underdog Moneyline: +172)
• 7/1/2026: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 6/30/2026: 7-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/29/2026: 5-3 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/24/2026: 6-5 MIL (Favorite: Brewers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 6/23/2026: 2-0 MIL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/22/2026: 2-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 9.5, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 9/28/2025: 4-2 MIL (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/27/2025: 7-4 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 9/26/2025: 3-1 CIN (Favorite: Brewers, Spread: -1.5, Total: 8, Favorite Moneyline: -172, Underdog Moneyline: +144)

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