Brewers vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for June 6

Odds updated as of 6:11 p.m.

The Milwaukee Brewers versus the San Diego Padres is on the MLB schedule for Friday.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Brewers vs Padres Game Info

• Milwaukee Brewers (34-29) vs. San Diego Padres (35-26)
• Date: Friday, June 6, 2025
• Time: 8:10 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and SDPA

Brewers vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-148) | SD: (+126)
• Spread: MIL: -1.5 (+136) | SD: +1.5 (-164)
• Total: 8.5 -- Over: (-120) | Under: (-102)

Brewers vs Padres Probable Starting Pitchers

Probable Pitchers: Chad Patrick (Brewers) - 3-4, 2.97 ERA vs Randy Vasquez (Padres) - 3-4, 3.99 ERA

The Brewers will look to Chad Patrick (3-4) against the Padres and Randy Vasquez (3-4). Patrick and his team have a record of 6-5-0 against the spread when he starts. Patrick's team has been victorious in 50% of the games he's started as the moneyline favorite with a record of 3-3. The Padres have a 6-5-0 ATS record in Vasquez's 11 starts with a set spread. The Padres are 2-5 in Vasquez's seven starts this season that they were the moneyline underdog.

Brewers vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (50.4%)

Brewers vs Padres Moneyline

• Milwaukee is a -148 favorite on the moneyline, while San Diego is a +126 underdog on the road.

Brewers vs Padres Spread

• The Brewers are hosting the Padres and are favored by 1.5 runs (+136 to cover) on the runline. San Diego is -164 to cover.

Brewers vs Padres Over/Under

• Brewers versus Padres, on June 6, has an over/under of 8.5, with the over being -120 and the under -102.

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Brewers vs Padres Betting Trends

• The Brewers have been chosen as favorites in 30 games this year and have walked away with the win 21 times (70%) in those games.
• This season Milwaukee has come away with a win seven times in eight chances when named as a favorite of at least -148 on the moneyline.
• The Brewers and their opponents have gone over the total this season in 25 of their 62 opportunities.
• The Brewers have an against the spread record of 34-28-0 in 62 games with a line this season.
• The Padres have gone 12-12 in games they were listed as the moneyline underdog (winning 50% of those games).
• San Diego has gone 5-6 when playing as a moneyline underdog with odds of +126 or longer (45.5%).
• In the 60 games oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 25 times (25-33-2).
• The Padres have collected a 31-29-0 record against the spread this season (covering 51.7% of the time).

Brewers Player Leaders

• Jackson Chourio leads Milwaukee with a slugging percentage of .446, fueled by 29 extra-base hits. He has a .260 batting average and an on-base percentage of .286.
• Among the qualifying hitters in the majors, his batting average ranks 76th, his on-base percentage ranks 145th, and he is 60th in slugging.
• Christian Yelich has five doubles, 13 home runs and 24 walks. He's batting .237 and slugging .430 with an on-base percentage of .316.
• His batting average ranks 117th among qualified players, his on-base percentage 97th, and his slugging percentage 72nd.
• Yelich heads into this game looking to extend his three-game hit streak. During his last five outings he is hitting .421 with a home run and three RBIs.
• Brice Turang has collected 62 base hits, an OBP of .358 and a slugging percentage of .366 this season.
• Turang takes a two-game hitting streak into this matchup. In his last five games he is batting .375 with two doubles, four walks and three RBIs.
• Sal Frelick has been key for Milwaukee with 62 hits, an OBP of .352 plus a slugging percentage of .404.

Padres Player Leaders

• Manny Machado has racked up 72 hits with a .382 on-base percentage and a .498 slugging percentage, all club-highs for the Padres. He's batting .317.
• Including all qualifying players in the big leagues, his batting average places him 10th, his on-base percentage ranks 17th, and he is 25th in slugging.
• Machado heads into this game on a three-game hitting streak. In his last five games he is batting .421 with two home runs, two walks and six RBIs.
• Fernando Tatis Jr. is hitting .268 with eight doubles, a triple, 13 home runs and 25 walks. He's slugging .477 with an on-base percentage of .340.
• Including all qualified hitters, he ranks 63rd in batting average, 61st in on-base percentage and 43rd in slugging percentage.
• Luis Arraez is hitting .282 with 12 doubles, three triples, three home runs and 11 walks.
• Gavin Sheets is hitting .263 with seven doubles, a triple, 11 home runs and 14 walks.

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