Brewers vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for May 6

Odds updated as of 7:11 a.m.

The Milwaukee Brewers are among the MLB squads busy on Tuesday, up against the Houston Astros.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information regarding this matchup.

Brewers vs Astros Game Info

• Milwaukee Brewers (18-18) vs. Houston Astros (17-17)
• Date: Tuesday, May 6, 2025
• Time: 7:40 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: FDSWI and SCHN

Brewers vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: MIL: (-108) | HOU: (-108)
• Spread: MIL: +1.5 (-194) | HOU: -1.5 (+160)
• Total: 8 -- Over: (-110) | Under: (-110)

Brewers vs Astros Probable Starting Pitchers

Probable Pitchers: Chad Patrick (Brewers) - 1-3, 2.87 ERA vs Hayden Wesneski (Astros) - 1-2, 3.86 ERA

This contest's pitching matchup is set, as the Brewers will send Chad Patrick (1-3) to the mound, while Hayden Wesneski (1-2) will get the nod for the Astros. Patrick and his team are 4-2-0 ATS this season when he starts. Patrick's team has a record of 2-2 this season when he starts and they are the favorite on the moneyline. The Astros have a 3-2-0 ATS record in Wesneski's five starts that had a set spread. The Astros are 1-2 in Wesneski's three starts this season that they were the underdog on the moneyline.

Brewers vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (50.4%)

Brewers vs Astros Moneyline

• Milwaukee is the favorite, -108 on the moneyline, while Houston is a -108 underdog on the road.

Brewers vs Astros Spread

Brewers vs Astros Over/Under

• An over/under of 8 has been set for Brewers-Astros on May 6, with the over being -110 and the under -110.

Bet on Milwaukee Brewers vs. Houston Astros on FanDuel today!

Brewers vs Astros Betting Trends

• The Brewers have won in 13, or 72.2%, of the 18 contests they have been named as odds-on favorites in this year.
• This year Milwaukee has won 14 of 19 games when listed as at least -108 on the moneyline.
• Contests with the Brewers have gone over the total set by oddsmakers in 15 of 36 chances this season.
• The Brewers are 21-15-0 against the spread in their 36 games that had a posted line this season.
• The Astros have won 55.6% of the games this season they were the underdog on the moneyline (5-4).
• When it has played as a moneyline underdog with odds of -108 or longer, Houston has a record of 5-4 (55.6%).
• The Astros have played in 34 games with an over/under set, and have combined with opponents to go over the total 15 times (15-17-2).
• The Astros have covered 52.9% of their games this season, going 18-16-0 against the spread.

Brewers Player Leaders

• Jackson Chourio has 39 hits, which is best among Milwaukee hitters this season, while batting .255 with 19 extra-base hits. He has an on-base percentage of .268 and a slugging percentage of .464.
• Among qualifying hitters in the majors, he ranks 72nd in batting average, 142nd in on-base percentage, and 47th in slugging.
• Chourio will look for his fourth straight game with a hit in this matchup. During his last five outings he is batting .150 with a double.
• Brice Turang leads Milwaukee in slugging percentage (.400) thanks to five extra-base hits. He's batting .315 with an on-base percentage of .372.
• His batting average is 11th among qualified players, his on-base percentage 32nd, and his slugging percentage 87th.
• William Contreras has 30 hits this season and has a slash line of .248/.361/.339.
• Contreras has recorded at least one base hit in two games in a row. During his last five outings he is batting .176 with two walks and an RBI.
• Christian Yelich has six home runs, 25 RBI and a batting average of .210 this season.
• Yelich brings a two-game hitting streak into this game. During his last five outings he is hitting .100 with a home run, a walk and two RBI.

Astros Player Leaders

• Jeremy Pena has put up a slugging percentage of .414 and has 36 hits, both team-high numbers for the Astros. He's batting .281 and with an on-base percentage of .345.
• He is 39th in batting average, 60th in on-base percentage and 75th in slugging percentage among all qualifying batters in the big leagues.
• Pena hopes to build on a nine-game hitting streak in this matchup. During his last 10 outings he is batting .341 with two doubles, a home run, two walks and four RBI.
• Isaac Paredes paces his team with a .357 on-base percentage. He has a batting average of .258 while slugging .395.
• Including all qualifying hitters, his batting average places him 68th, his on-base percentage is 47th, and he is 95th in slugging.
• Jose Altuve is batting .259 with four doubles, four home runs and nine walks.
• Jake Meyers has five doubles, a triple, two home runs and eight walks while hitting .301.

Brewers vs Astros Head to Head

• 5/5/2025: 5-1 MIL (Favorite: Brewers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/19/2024: 9-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/18/2024: 4-2 MIL (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 5/17/2024: 5-4 HOU (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/24/2023: 4-0 MIL (Favorite: Brewers, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 5/23/2023: 6-0 MIL (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/22/2023: 12-2 HOU (Favorite: Brewers, Spread: -1.5, Total: 7.5, Favorite Moneyline: -108, Underdog Moneyline: -108)

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