Blue Jays vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 11

Odds updated as of 12:11 a.m.

The MLB schedule on Thursday includes the Toronto Blue Jays taking on the Houston Astros.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Blue Jays vs Astros Game Info

• Toronto Blue Jays (83-62) vs. Houston Astros (79-67)
• Date: Thursday, September 11, 2025
• Time: 3:07 p.m. ET
• Venue: Rogers Centre -- Toronto, Ontario
• Coverage: MLB Network, SNET, and SCHN

Blue Jays vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TOR: (-162) | HOU: (+136)
• Spread: TOR: -1.5 (+126) | HOU: +1.5 (-152)
• Total: 8.5 -- Over: (-106) | Under: (-114)

Blue Jays vs Astros Probable Starting Pitchers

Probable Pitchers: Kevin Gausman (Blue Jays) - 9-10, 3.63 ERA vs Cristian Javier (Astros) - 1-2, 4.43 ERA

The probable pitchers are Kevin Gausman (9-10) for the Blue Jays and Cristian Javier (1-2) for the Astros. Gausman's team is 13-15-0 against the spread this season in his starts. Gausman's team has been victorious in 38.5% of the games he's started as the moneyline favorite with a record of 5-8. The Astros have a 2-3-0 ATS record in Javier's five starts with a set spread. The Astros have a 2-1 record in Javier's three starts this season when they were the underdog on the moneyline.

Blue Jays vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Blue Jays win (53.7%)

Blue Jays vs Astros Moneyline

• Looking at the moneyline for Blue Jays-Astros, Toronto is the favorite at -162, and Houston is +136 playing on the road.

Blue Jays vs Astros Spread

• The Blue Jays are hosting the Astros and are favored by 1.5 runs on the spread. The Blue Jays are +126 to cover the runline, with the Astros being -152.

Blue Jays vs Astros Over/Under

• Blue Jays versus Astros, on Sept. 11, has an over/under of 8.5, with the over being -106 and the under -114.

Bet on Toronto Blue Jays vs. Houston Astros on FanDuel today!

Blue Jays vs Astros Betting Trends

• The Blue Jays have been favorites in 68 games this season and have come away with the win 39 times (57.4%) in those contests.
• Toronto has a record of 18-6 when favored by -162 or more this year.
• The Blue Jays and their opponents have gone over in 79 of their 144 games with a total set by sportsbooks this season.
• The Blue Jays have an against the spread mark of 84-60-0 in 144 games with a line this season.
• The Astros have won 29 of the 51 games they were listed as the moneyline underdog this season (56.9%).
• Houston has played four times as a moneyline underdog with odds of +136 or longer, and earned a victory in each game.
• The Astros have combined with opponents to go over the total 65 times this season for a 65-76-4 record against the over/under.
• The Astros have a 72-73-0 record ATS this season.

Blue Jays Player Leaders

• Vladimir Guerrero Jr. has 158 hits this season and a team-best OBP of .393. He has a .302 batting average and a slugging percentage of .496.
• Among all qualifying hitters in MLB, he ranks fifth in batting average, third in on-base percentage, and 22nd in slugging.
• George Springer has 128 hits, which is tops among Toronto batters this season. He's batting .297 with 50 extra-base hits. He's also slugging .545 with an on-base percentage of .390.
• Among qualified batters, his batting average places him seventh, his on-base percentage fifth, and his slugging percentage seventh.
• Ernie Clement is batting .278 with a .401 slugging percentage and 42 RBI this year.
• Clement has recorded at least one base hit in five games in a row. During his last five outings he is hitting .412 with four doubles, two walks and an RBI.
• Alejandro Kirk is batting .289 with a .357 OBP and 65 RBI for Toronto this season.

Astros Player Leaders

• Jose Altuve has a .439 slugging percentage, which leads the Astros. He's batting .263 with an on-base percentage of .327.
• Including all the qualified players in the big leagues, he is 63rd in batting average, 81st in on-base percentage and 72nd in slugging percentage.
• Jeremy Pena's 138 hits and .358 OBP are both team-highs. He has a batting average of .299 while slugging .464.
• He is currently sixth in batting average, 23rd in on-base percentage and 44th in slugging percentage among all qualifying hitters.
• Yainer Diaz has 22 doubles, a triple, 19 home runs and 20 walks while batting .256.
• Carlos Correa is hitting .276 with 24 doubles, 13 home runs and 38 walks.

Blue Jays vs Astros Head to Head

• 9/10/2025: 3-2 HOU (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 9/9/2025: 4-3 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -152, Underdog Moneyline: +128)
• 4/23/2025: 3-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/22/2025: 5-1 HOU (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/21/2025: 7-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/4/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/3/2024: 9-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/2/2024: 7-6 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/1/2024: 3-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/3/2024: 8-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!